TDGF1 抗体
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北京 101111
Quick Overview for TDGF1 抗体 (ABIN1846225)
抗原
See all TDGF1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Ascitic fluid containing 0.03% sodium azide.
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免疫原
- Purified recombinant fragment of human TDGF1 expressed in E. Coli.
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亚型
- IgG1
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限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C.
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- TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
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别名
- TDGF1
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背景
- This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
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分子量
- 21 kDa
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途径
- EGFR Signaling Pathway
抗原
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