BMPR1A 抗体 (AA 179-378)
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Quick Overview for BMPR1A 抗体 (AA 179-378) (ABIN1845272)
抗原
See all BMPR1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 179-378
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human BMPR1A (AA: 179-378) expressed in E. coli.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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别名
- BMPR1A
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背景
- The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2.These receptors are also closely related to the activin receptors, ACVR1 and ACVR2.The ligands of these receptors are members of the TGF-beta superfamily.TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD.Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
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分子量
- 60 kDa
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基因ID
- 657
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UniProt
- P36894
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途径
- Stem Cell Maintenance
抗原
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