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Doublecortin 抗体 (AA 362-411)

This anti-Doublecortin antibody is a 小鼠 单克隆 antibody detecting Doublecortin in WB, ELISA, IHC, FACS 和 IF/ICC. Suitable for 人.
产品编号 ABIN1844030
发货至: 中国

Quick Overview for Doublecortin 抗体 (AA 362-411) (ABIN1844030)

抗原

See all Doublecortin (DCX) 抗体
Doublecortin (DCX)

适用

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宿主

  • 95
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小鼠

克隆类型

  • 92
  • 21
单克隆

标记

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This Doublecortin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)
  • 抗原表位

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    AA 362-411

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human DCX (AA: 362-411) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    Doublecortin (DCX)

    别名

    DCX

    背景

    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

    分子量

    49.3 kDa

    基因ID

    1641

    UniProt

    O43602
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