ACLY 抗体 (AA 306-502)
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北京 101111
Quick Overview for ACLY 抗体 (AA 306-502) (ABIN1842880)
抗原
See all ACLY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 306-502
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human ACLY (AA: 306-502) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- ACLY (ATP Citrate Lyase (ACLY))
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别名
- ACLY
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背景
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
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分子量
- 125 kDa
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基因ID
- 47
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UniProt
- P53396
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途径
- Warburg Effect
抗原
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