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APOA5 抗体 (AA 20-363)

This 小鼠 单克隆 antibody specifically detects APOA5 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN1842850
发货至: 中国
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Quick Overview for APOA5 抗体 (AA 20-363) (ABIN1842850)

抗原

See all APOA5 抗体
APOA5 (Apolipoprotein A-V (APOA5))

适用

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宿主

  • 68
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小鼠

克隆类型

  • 72
  • 19
单克隆

标记

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This APOA5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 20-363

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    APOA5 (Apolipoprotein A-V (APOA5))

    别名

    Apoa5

    背景

    Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

    分子量

    41 kDa

    基因ID

    116519

    UniProt

    Q6Q788

    途径

    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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