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APOA5 抗体 (AA 20-363)

APOA5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN1842850
发货至: 中国
  • 抗原 See all APOA5 抗体
    APOA5 (Apolipoprotein A-V (APOA5))
    抗原表位
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 20-363
    适用
    • 65
    • 25
    • 22
    • 2
    • 1
    • 1
    宿主
    • 56
    • 17
    • 1
    小鼠
    克隆类型
    • 58
    • 17
    单克隆
    标记
    • 39
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOA5 antibody is un-conjugated
    应用范围
    • 43
    • 23
    • 21
    • 13
    • 12
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. Coli.
    亚型
    IgG1
    Top Product
    Discover our top product APOA5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原
    APOA5 (Apolipoprotein A-V (APOA5))
    别名
    Apoa5 (APOA5 产品)
    背景
    Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
    分子量
    41 kDa
    基因ID
    116519
    UniProt
    Q6Q788
    途径
    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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