APOA5 抗体 (AA 20-363)
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Quick Overview for APOA5 抗体 (AA 20-363) (ABIN1842850)
抗原
See all APOA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-363
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. Coli.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- APOA5 (Apolipoprotein A-V (APOA5))
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别名
- Apoa5
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背景
- Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
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分子量
- 41 kDa
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基因ID
- 116519
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UniProt
- Q6Q788
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途径
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
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