TIAM1 抗体 (N-Term)
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Quick Overview for TIAM1 抗体 (N-Term) (ABIN1841841)
抗原
See all TIAM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Rabbit antibody to TIAM 1
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特异性
- Specific for TIAM1.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from n-terminal region of human T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 TIAM1) conjugated to an immunogenic carrier protein was used as the antigen.
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亚型
- IgG
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应用备注
- IHC WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))
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别名
- TIAM 1
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背景
- FUNCTION: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1 CDC42 and to a lesser extent RHOA. SUBUNIT: Interacts with BAIAP2. TISSUE SPECIFICITY: Found in virtually all analyzed tumor cell lines including B- and T-lymphomas neuroblastomas melanomas and carcinomas.
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UniProt
- Q13009
抗原
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