Asialoglycoprotein Receptor 1 抗体
Quick Overview for Asialoglycoprotein Receptor 1 抗体 (ABIN1839609)
抗原
See all Asialoglycoprotein Receptor 1 (ASGR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The asialoglycoprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kD) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediates the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed.
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纯化方法
- Purified
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免疫原
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Crude rat liver membrane extracts.
Type of Immunogen: Membrane extract -
亚型
- IgG1
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应用备注
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Approved: Flo, IHC, IHC-Fr, WB
Usage: For use in Western blot, non-reducing conditions are required. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.02 % sodium azide, 0.1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4°C.
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- Asialoglycoprotein Receptor 1 (ASGR1)
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别名
- ASGR1 / ASGPR
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背景
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Name/Gene ID: ASGR1
Synonyms: ASGR1, ASGPR1, ASGPR, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1, HL-1, ASGP-R 1, CLEC4H1 -
基因ID
- 432
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UniProt
- P07306
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途径
- Thyroid Hormone Synthesis
抗原
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