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EpCAM 抗体

EPCAM 适用: 人 FACS, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HEA-125 unconjugated
产品编号 ABIN1838157
发货至: 中国
  • 抗原 See all EpCAM (EPCAM) 抗体
    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EpCAM antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes the 34kD cell surface antigen known as CD326 or Epithelial Cell Adhesion Molecule (Ep-CAM). This antigen has been identified independently by a number of groups, and it has been known by a variety of names including Epithelial Specific Antigen, MOC31 and Ber-EP4. Several monoclonal antibodies have been raised against Ep-CAM, many of which have been described as tumor specific molecules on carcinomas. Ep-CAM is a Type 1 transmembrane glycoprotein. It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells. Ep-CAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumor cells, and de novo expression being seen in dysplastic squamous epithelium.
    纯化方法
    Purified
    免疫原
    HT29 carcinoma cell line.

    Type of Immunogen: Cells
    克隆位点
    HEA-125
    亚型
    IgG1
    Top Product
    Discover our top product EPCAM Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide. 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
    别名
    ESA / EPCAM (EPCAM 产品)
    背景
    Name/Gene ID: EPCAM

    Synonyms: EPCAM, 323/A3, ACSTD1, 17-1A, CD326, EGP, EGP34, Epithelial glycoprotein, GA733-2, HNPCC8, Ep-CAM, ESA, HEGP314, KS 1/4 antigen, KS1/4, KSA, M1S2, MIC18, MK-1, MH99, TROP1, TACST-1, TACSTD1, CD326 antigen, CO-17A, DIAR5, EGP-2, EGP314, EGP40, Epithelial glycoprotein 314, HEA125, Ly74, M4S1
    基因ID
    4072
    UniProt
    P16422
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