ITGAL 抗体
Quick Overview for ITGAL 抗体 (ABIN1837566)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin 9-2). A defect in 9-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections.
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纯化方法
- Purified
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4°C.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- LFA-1 / CD11A
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背景
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Name/Gene ID: ITGAL
Family: Integrin
Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A -
基因ID
- 3683
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UniProt
- P20701
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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