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ITGAL 抗体

This anti-ITGAL antibody is a 小鼠 单克隆 antibody detecting ITGAL in FACS, IHC 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN1837566
发货至: 中国

Quick Overview for ITGAL 抗体 (ABIN1837566)

抗原

See all ITGAL 抗体
ITGAL (Integrin alpha-L (ITGAL))

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGAL antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

87-6F9
  • 特异性

    CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin 9-2). A defect in 9-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections.

    纯化方法

    Purified

    免疫原



    Type of Immunogen: Native protein

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 4°C.
  • 抗原

    ITGAL (Integrin alpha-L (ITGAL))

    别名

    LFA-1 / CD11A

    背景

    Name/Gene ID: ITGAL
    Family: Integrin

    Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

    基因ID

    3683

    UniProt

    P20701

    途径

    Activated T Cell Proliferation, Integrin Complex
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