CCL24 抗体
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北京 101111
Quick Overview for CCL24 抗体 (ABIN182117)
抗原
See all CCL24 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Eotaxin-2.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Recombinant mouse Eotaxin-2
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (AA 27-119) antibody
CCL24 适用: 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (AA 27-119) antibodyCCL24 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (C-Term) antibodyCCL24 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (AA 27-119) antibodyCCL24 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 3# unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) antibodyCCL24 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (AA 27-119) antibodyCCL24 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (C-Term) antibodyCCL24 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (AA 1-119) antibodyCCL24 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) antibody (HRP)CCL24 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
anti-Chemokine (C-C Motif) Ligand 24 (CCL24) (AA 27-119) antibodyCCL24 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity of mEotaxin-2 (100 ng/mL), a concentration of 7.0 - 8.0 μg/mL of this antibody is required. ELISA: Indirect: To detect mEotaxin-2 (using 100 m l/well antibody solution) a concentration of 0.5 - 2.0 m g/mL of this antibody is required. In conjunction with compatible secondary reagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant mEotaxin-2. Sandwich: To detect mEotaxin-2 (using 100 m l/well antibody solution) a concentration of 0.5 - 2.0 m g/mL of this antibody is required. In conjunction with Biotinylated Anti-Murine Eotaxin-2 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant mEotaxin-2. Western blot: To detect mEotaxin-2 this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant mEotaxin-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- PBS, pH 7.2
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储存条件
- -20 °C
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储存方法
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Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeksat2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C. Avoid repeatedfreezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))
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别名
- Eotaxin-2 / CCL24
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背景
- Eotaxin 2 is a member of the CC chemokine family, based on the presence of the CC motif and homology with other known CC chemokines. Eotaxin 2 cDNA encodes a 119 amino acid residue precursor protein with a 26 amino acid residue signal peptide that is cleaved to generate a mature protein predicted to contain 93 amino acid residues with an N glycosylation site. Mature human eotaxin 2 has a predicted molecular mass of approximately 10.6 kDa. Compared to other CC chemokines, eotaxin 2 exhibits 40 %, 42 %, and 39 % amino acid identity to MCP3, MIP1 alpha, and eotaxin, respectively. Human CC chemokine eotaxin 2 maps to chromosome 7q11.23. Both eotaxin and eotaxin 2 activate and attract eosinophils and basophils. A receptor for human eotaxin has been identified and found to be the third numbered receptor in the C-C chemokine subfamily of receptors (CCR3. On eosinophils, the effects of eotaxin 2 is inhibited by an CCR3 antibody and cross-desensitized by eotaxin and MCP4, suggesting that all three CC chemokines act through CCR3. Eotaxin 2 mRNA is weakly expressed in activated monocytes and T lymphocytes. Recombinant eotaxin 2 induces chemotaxis of eosinophils, basophils, and resting T lymphocytes but not monocytes and activated T lymphocytes. Eotaxin 2 inhibits colony formation in myleloid progenitor cells.Synonyms: C-C motif chemokine 24, CK-beta-6, Eosinophil chemotactic protein 2, MPIF-2, MPIF2, Myeloid progenitor inhibitory factor 2, SCYA24, Small-inducible cytokine A24
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基因ID
- 56221
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UniProt
- Q9JKC0
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途径
- Regulation of Actin Filament Polymerization
抗原
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