IL-2 抗体
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北京 101111
Quick Overview for IL-2 抗体 (ABIN182113)
抗原
See all IL-2 (IL2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognises ovine interleukin-2 (IL-2). No cross-reactivity is seen with ovine IL-1b, IL-6, IL-8, MCP-1 or TNF alpha.
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纯化方法
- None
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免疫原
- Recombinant ovine IL-2
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应用备注
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Western blot. ELISA (1/500 detection, use ABIN119103 as coating antibody, It is recommended that ABIN182113 and any detection reagent are diluted in 10 % normal mouse serum prior to use in ELISA).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Serum stabilized by PBS and 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store at 2-8 °C or at -20 °C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: One year from despatch. -
有效期
- 12 months
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- IL-2 (IL2) (Interleukin 2 (IL2))
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别名
- Interleukin-2 / IL2
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背景
- Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF
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基因ID
- 443401
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UniProt
- P19114
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
抗原
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