Sialoadhesin/CD169 抗体 (FITC)
Quick Overview for Sialoadhesin/CD169 抗体 (FITC) (ABIN1820283)
抗原
See all Sialoadhesin/CD169 (SIGLEC1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for CD169, also known as sialoadhesin. The antibody reacts with a subpopulation of mature resident tissue macrophages. No reactivity is seen with dendritic cells, peritoneal resident macrophages, peritoneal exudate cells or blood cells. Distinct macrophage subpopulations of lymphoid organs express the antigen. In the spleen, they are localized at the marginal sinus forming a ring around the periarteriolar lymphocyte sheath and follicular areas at the inner side of marginal zones. In lymph nodes, they are localized in the sinusoids and medullary cords but not within follicular areas or paracortex. In Peyer's patches they are localized in the interfollicular areas at the serosal side. Kupffer cells in the liver can be clearly stained by MOMA-1, although antigen expression is weaker than that seen in splenic macrophages. No MOMA-1 positive macrophages were found in the thymus. Reactivity was also negative in following organs tested so far (kidney, brain, skin). In non-lymphoid organs, the antigen is only found on a macrophage subpopulation in the lamina propria of the villi of the small intestine.
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无交叉反应
- 人, 大鼠
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纯化方法
- Protein G purified
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免疫原
- Stromal (reticular) elements from spleen.
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亚型
- IgG2a
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应用备注
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Approved: Flo (1:1), IF
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide, 1 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Protect from light.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
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别名
- SIGLEC1 / CD169 / Sialoadhesin
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背景
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Name/Gene ID: SIGLEC1
Family: Immunoglobulin
Synonyms: SIGLEC1, CD169, CD169 antigen, SIGLEC-1, Sialoadhesin, SN, DJ1009E24.1 -
基因ID
- 6614
抗原
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