Lipoprotein Lipase 抗体 (AA 380-410)
Quick Overview for Lipoprotein Lipase 抗体 (AA 380-410) (ABIN1820141)
抗原
See all Lipoprotein Lipase (LPL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 380-410
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特异性
- Recognizes an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues. A deficiency of LPL can result in hypertriglyceridemia, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Clone 5D2 has been shown to inhibit the activity of human LPL(2,3), and is widely used in human studies.
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无交叉反应
- 小鼠
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纯化方法
- Protein G purified
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免疫原
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Purified bovine milk lipoprotein lipase.
Type of Immunogen: Purified protein -
亚型
- IgG1
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anti-Lipoprotein Lipase (LPL) (AA 28-474) antibody
LPL 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein Lipase (LPL) (AA 300-327) antibodyLPL 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein Lipase (LPL) (AA 55-316) antibodyLPL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein Lipase (LPL) antibodyLPL 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein Lipase (LPL) (AA 162-246) antibodyLPL 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein Lipase (LPL) antibody (HRP)LPL 适用: 人, 大鼠, Cow, 小鸡, 豚鼠 WB, IP, ELISA 宿主: 小鼠 Monoclonal 5D2 HRP
anti-Lipoprotein Lipase (LPL) (AA 1-475) antibodyLPL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein Lipase (LPL) antibodyLPL 适用: 人, 大鼠, 小鼠, Golden Syrian Hamster, Cat WB, ELISA, FACS, IF, InhA 宿主: 小鼠 Monoclonal 5D2 unconjugated
anti-Lipoprotein Lipase (LPL) antibodyLPL 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Lipoprotein Lipase (LPL) (AA 300-327) antibodyLPL 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Bovine
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Lipoprotein Lipase (LPL)
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别名
- Lipoprotein Lipase / LPL
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背景
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Name/Gene ID: LPL
Synonyms: LPL, LIPD, Lipoprotein lipase, HDLCQ11 -
基因ID
- 4023
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途径
- Lipid Metabolism
抗原
-
