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APOE 抗体 (AA 140-160) (Biotin)

This anti-APOE antibody is a 小鼠单克隆 antibody detecting APOE in WB 和 ELISA. Suitable for 人.

产品编号 ABIN1820137

发货至: 中国

Datasheet as PDF

Quick Overview for APOE 抗体 (AA 140-160) (Biotin) (ABIN1820137)

抗原

See all APOE 抗体

APOE (Apolipoprotein E (APOE))

适用

110
86
74
4
4
2
2
1
1
1

人

宿主

小鼠

克隆类型

单克隆

标记

98
17
11
6
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1

This APOE antibody is conjugated to Biotin

应用范围

145
69
60
47
44
39
39
22
13
12
9
6
5
2
2
2
2
2
2
1
1

Western Blotting (WB), ELISA

克隆位点

WUE-4

Discover our top product APOE Primary Antibody

抗原表位
15

15

15

11

6

6

6

5

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 140-160

特异性

Recognizes an epitope within amino acids 140-160 of human apolipoprotein E (Apo-E), a major component of very low-density lipoproteins (VLDLs). Apo-E is the principle apolipoprotein in the central nervous system, and is secreted by most organs into the plasma, playing a vital role in the binding, internalization and catabolism of triglyceride-rich lipoprotein constituents. Apo-E acts as a ligand for both the specific apo-E receptor (chylomicron remnant) of hepatic tissues, and the apoB, E (LDL) receptor. Three isoforms of Apo-E have been identified, ApoE2, E3 and E4, and have been linked with various disorders. ApoE2 has been shown to bind LPL receptors with low affinity, resulting in increased plasma cholesterol and triglyceride levels, and thereby an increased risk in cardiovascular disorders. ApoE4 is a known high risk factor for Alzheimer's disease, and in particular late onset Alzheimer disease 2 (AD2), whilst ApoE3 is the most common isoform, and considered the normal/natural Apo-E genotype. Clone 6-4 has been shown to inhibit Apo-E mediated binding of lipoproteins to the apoB, E cell receptor.

纯化方法

Protein G purified

免疫原

Purified ApoHDL fraction.

Type of Immunogen: Purified protein

亚型

IgG1
anti-Apolipoprotein E (APOE) (AA 19-181) antibody
APOE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 19-168) antibody
APOE 适用: 大鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 1-172) antibody
APOE 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 19-168) antibody
APOE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated

anti-Apolipoprotein E (APOE) (C-Term) antibody
APOE 适用: 人 WB, ELISA, IP, ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 200-300) antibody
APOE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) antibody
APOE 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1H4 unconjugated

anti-Apolipoprotein E (APOE) (N-Term) antibody
APOE 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 151-250) antibody
APOE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apolipoprotein E (APOE) (AA 14-167) antibody
APOE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Approved: ELISA, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

说明

Target Species of Antibody: Human

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

PBS, 0.09 % sodium azide, 1 % BSA

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

4°C or -20°C, Avoid freeze-thaw cycles.
抗原

APOE (Apolipoprotein E (APOE))

别名

APOE / Apolipoprotein E

背景

Name/Gene ID: APOE

Synonyms: APOE, AD2, Apo-E, Apolipoprotein E3, Apolipoprotein E, LDLCQ5, LPG

基因ID

348

UniProt

P02649

途径

Regulation of Cell Size, Lipid Metabolism

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