TREM2 抗体
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- 抗原 See all TREM2 抗体
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This TREM2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- Recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
- 纯化方法
- Protein G purified
- 内毒素水平
- Low Endotoxin
- 免疫原
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Mouse TREM-2 Fc fusion protein.
Type of Immunogen: Fusion protein - 克隆位点
- 78-18
- 亚型
- IgG1
- Top Product
- Discover our top product TREM2 Primary Antibody
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- 应用备注
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Approved: Flo (1:25 - 1:200), Func
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze-thaw cycles.
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- 抗原
- TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
- 别名
- TREM2 / TREM-2 (TREM2 产品)
- 背景
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Name/Gene ID: TREM2
Synonyms: TREM2, Trem2b, TREM-2, Trem2a, Trem2c - 基因ID
- 54209
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