ABCA1 抗体 (PE)
Quick Overview for ABCA1 抗体 (PE) (ABIN1819886)
抗原
See all ABCA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease. Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.
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纯化方法
- Protein G purified
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免疫原
- ABCA1 transfected HeLa cells.
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亚型
- IgG2a
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应用备注
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Approved: Flo (1:1)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Distilled water
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Protect from light.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
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- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
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别名
- ABCA1
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背景
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Name/Gene ID: ABCA1
Subfamily: ATP-binding cassette - ABCA/ABC1
Family: Transporter
Synonyms: ABCA1, ABC-1, ABC1, CERP, HDLDT1, Tangier disease, ATP-binding cassette 1, Td, Membrane-bound, TGD -
基因ID
- 19
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UniProt
- O95477
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
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