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CCR7 抗体 (AA 2-22)

CCR7 适用: 人, 小鼠 FACS, WB, ELISA, IHC, IHC (p), Func 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN1819309
发货至: 中国
  • 抗原 See all CCR7 抗体
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    抗原表位
    • 16
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-22
    适用
    • 99
    • 50
    • 36
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 74
    • 24
    • 12
    • 4
    山羊
    克隆类型
    • 66
    • 47
    • 1
    多克隆
    标记
    • 52
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR7 antibody is un-conjugated
    应用范围
    • 59
    • 52
    • 23
    • 20
    • 17
    • 15
    • 15
    • 14
    • 14
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
    特异性
    Recognizes mouse C-C chemokine receptor type 7, also known as CD197, CCR7, Epstein-Barr virus-induced G-protein coupled receptor 1 or MIP-3 beta receptor. CD197 is a 378 amino acid ~43 kD multi pass type III transmembrane glycoprotein and member of the G-protein coupled receptor 1 family. CD197 is expressed by various lymphoid tissues, activated B and T cells, naive T cells, NK cells and dendritic cells (DCs), which acts a high-affinity receptor for the chemokines MIP-3beta (CCL19) and CCL21. Ligand binding of CD197 plays a vital role in the homing of naive T cells and antigen-loaded DCs into secondary organs. Expression of CD197 is strongly up-regulated in B cells infected with Epstein-Barr virus (EBV) and T cells infected with herpesvirus 6 or 7. Can be used in research studies to distinguish between central memory and effector memory T cells and is reported as suitable for use in immunocytochemistry.
    纯化方法
    Affinity purified
    免疫原
    Synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of mouse CD197. Percent identity by BLAST analysis: Mouse (100%), Rat, Hamster, Bovine (90%), Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (86%), Orangutan, Galago, Ferret, Dog, Cat, Horse (81%).

    Type of Immunogen: Synthetic peptide
    亚型
    IgG
    Top Product
    Discover our top product CCR7 Primary Antibody
  • 应用备注
    Approved: ELISA (1:100000), Flo (1:10), Func, IHC, IHC-P (1:250), WB (1:1000)
    说明

    Target Species of Antibody: Mouse

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.1 % sodium azide, 0.1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    别名
    CCR7 (CCR7 产品)
    背景
    Name/Gene ID: CCR7
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CCR7, BLR2, Chemokine (C-C) receptor 7, CD197, C-C CKR-7, CMKBR7, CC chemokine receptor 7, CCR-7, CD197 antigen, CDw197, EBI1, EVI1, MIP-3 beta receptor, C-c chemokine receptor 7, C-C chemokine receptor type 7, CC-CKR-7, Chemokine c-c motif receptor 7
    基因ID
    1236
    途径
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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