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CCR7 抗体 (AA 2-22)

This anti-CCR7 antibody is a 山羊 多克隆 antibody detecting CCR7 in FACS, WB, ELISA, IHC, IHC (p) 和 Func. Suitable for 人 和 小鼠.
产品编号 ABIN1819309
发货至: 中国

Quick Overview for CCR7 抗体 (AA 2-22) (ABIN1819309)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

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人, 小鼠

宿主

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山羊

克隆类型

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多克隆

标记

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This CCR7 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
  • 抗原表位

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    AA 2-22

    特异性

    Recognizes mouse C-C chemokine receptor type 7, also known as CD197, CCR7, Epstein-Barr virus-induced G-protein coupled receptor 1 or MIP-3 beta receptor. CD197 is a 378 amino acid ~43 kD multi pass type III transmembrane glycoprotein and member of the G-protein coupled receptor 1 family. CD197 is expressed by various lymphoid tissues, activated B and T cells, naive T cells, NK cells and dendritic cells (DCs), which acts a high-affinity receptor for the chemokines MIP-3beta (CCL19) and CCL21. Ligand binding of CD197 plays a vital role in the homing of naive T cells and antigen-loaded DCs into secondary organs. Expression of CD197 is strongly up-regulated in B cells infected with Epstein-Barr virus (EBV) and T cells infected with herpesvirus 6 or 7. Can be used in research studies to distinguish between central memory and effector memory T cells and is reported as suitable for use in immunocytochemistry.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of mouse CD197. Percent identity by BLAST analysis: Mouse (100%), Rat, Hamster, Bovine (90%), Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset (86%), Orangutan, Galago, Ferret, Dog, Cat, Horse (81%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: ELISA (1:100000), Flo (1:10), Func, IHC, IHC-P (1:250), WB (1:1000)

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.1 % sodium azide, 0.1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CCR7

    背景

    Name/Gene ID: CCR7
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CCR7, BLR2, Chemokine (C-C) receptor 7, CD197, C-C CKR-7, CMKBR7, CC chemokine receptor 7, CCR-7, CD197 antigen, CDw197, EBI1, EVI1, MIP-3 beta receptor, C-c chemokine receptor 7, C-C chemokine receptor type 7, CC-CKR-7, Chemokine c-c motif receptor 7

    基因ID

    1236

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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