SIGLEC10 抗体
Quick Overview for SIGLEC10 抗体 (ABIN1819172)
抗原
See all SIGLEC10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Clone 5G6 specifically recognizes human Siglec-10 (Sialic acid-binding Ig-like lectin 10), a putative adhesion molecule and member of the Ig superfamily, expressed by monocytes, B cells, eosinophils, and at a higher level by a subpopulation of CD16+CD56- natural killer (NK) cells. Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic acid. Studies have shown that Siglec-10 acts as a substrate for VAP-1 (Vascular adhesion protein-1), a glycoprotein expressed on endothelium during inflammation, which is involved in primary amine oxidation and leucocyte trafficking, see for details. This interaction between Siglec-10 and VAP-1, implicates Siglec-10 in endothelial lymphocyte adhesion and in the modulation of the inflammatory microenvironment. Studies have shown that clone 5G6 does not cross-react with Siglecs 3, 5, 7, 8 and 9, see for details.
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纯化方法
- Protein G purified
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免疫原
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Recombinant human Siglec-10, fused with the Fc region of human IgG.
Type of Immunogen: Recombinant protein -
亚型
- IgG1
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anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 571-697) antibody
SIGLEC10 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 571-697) antibodySIGLEC10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 589-696) antibodySIGLEC10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 589-696) antibodySIGLEC10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Extracellular Domain) antibody (PE)SIGLEC10 适用: 人 FACS 宿主: 小鼠 Monoclonal 5G6 PE
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (AA 321-420) antibodySIGLEC10 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Extracellular Domain) antibodySIGLEC10 适用: 人 ELISA, IHC, IP 宿主: 小鼠 Monoclonal 5G6 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) (Middle Region) antibodySIGLEC10 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
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别名
- SIGLEC10 / SIGLEC-10
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背景
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Name/Gene ID: SIGLEC10
Synonyms: SIGLEC10, SIGLEC-10, Siglec-like gene 2, Siglec-like protein 2, PRO940, SLG2 -
基因ID
- 89790
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UniProt
- Q96LC7
抗原
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