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CD300a 抗体 (PE)

CD300A 适用: 人 FACS 宿主: 小鼠 Monoclonal P192 PE
产品编号 ABIN1819155
发货至: 中国
  • 抗原 See all CD300a (CD300A) 抗体
    CD300a (CD300A)
    适用
    • 28
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    宿主
    • 15
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    • 5
    小鼠
    克隆类型
    • 17
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    单克隆
    标记
    • 17
    • 5
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    This CD300a antibody is conjugated to PE
    应用范围
    • 19
    • 14
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    • 1
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    Flow Cytometry (FACS)
    特异性
    Recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kD transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.
    纯化方法
    Protein G purified
    免疫原
    Polyclonal population of NK cells.

    Type of Immunogen: Cells
    克隆位点
    P192
    亚型
    IgG2a
    Top Product
    Discover our top product CD300A Primary Antibody
  • 应用备注
    Approved: Flo

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    Reconstitute with 1 mL distilled water.
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Protect from light.
    储存条件
    4 °C
    储存方法
    Store at 4°C. Do not freeze. Protect from light.
  • 抗原
    CD300a (CD300A)
    别名
    CD300A (CD300A 产品)
    背景
    Name/Gene ID: CD300A

    Synonyms: CD300A, CD300a antigen, CD300a molecule, CMRF35-like molecule 8, CMRF35-H, CMRF35-H9, CLM-8, CMRF35H9, IGSF12, Inhibitory receptor protein 60, IRC2, IRC1, NK inhibitory receptor, CMRF-35-H9, CMRF-35H, CMRF35H, IRC1a, IRp60, Leukocyte membrane antigen
    基因ID
    11314
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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