Lipoprotein Lipase 抗体 (AA 380-410) (HRP)
Quick Overview for Lipoprotein Lipase 抗体 (AA 380-410) (HRP) (ABIN1819130)
抗原
See all Lipoprotein Lipase (LPL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 380-410
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特异性
- Recognizes an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues. A deficiency of LPL can result in hypertriglyceridemia, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Clone 5D2 has been shown to inhibit the activity of human LPL(2,3), and is widely used in human studies.
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无交叉反应
- 小鼠
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纯化方法
- Protein G purified
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免疫原
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Purified bovine milk lipoprotein lipase.
Type of Immunogen: Purified protein -
亚型
- IgG1
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应用备注
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Approved: ELISA, IP, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Bovine
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.01 % Thiomersal, HRP Stabiliser
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 4°C. Do not freeze.
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- Lipoprotein Lipase (LPL)
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别名
- Lipoprotein Lipase / LPL
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背景
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Name/Gene ID: LPL
Synonyms: LPL, LIPD, Lipoprotein lipase, HDLCQ11 -
基因ID
- 4023
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途径
- Lipid Metabolism
抗原
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