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CD68 抗体 (PE)

This anti-CD68 antibody is a 大鼠 单克隆 antibody detecting CD68 in FACS. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN181838
发货至: 中国

Quick Overview for CD68 抗体 (PE) (ABIN181838)

抗原

See all CD68 抗体
CD68 (CD68 Molecule (CD68))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD68 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

FA-11
  • 特异性

    The antibody recognizes CD68. SM1550R does detect surface Macrosialin at low levels in resident Mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.

    纯化方法

    Affinity Chromatography on Protein G

    亚型

    IgG2a
  • 应用备注

    Flow cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL. Membrane permeabilisation is required for this application. ABIN181838 does detect surface macrosialin at low levels in resident mouse peritoneal macrophages which can be enhanced with thioglycollate stimulation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.0 mL distilled water.

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Kirby, Beattie, Maroof, van Rooijen, Kaye: "SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages." in: The American journal of pathology, Vol. 175, Issue 3, pp. 1107-15, (2009) (PubMed).

  • 抗原

    CD68 (CD68 Molecule (CD68))

    别名

    CD68

    背景

    Macrosialin is a heavily glycosylated transmembrane protein of 87-115kD, which is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. Macrosialin is the murine homologue of the human macrophage glycoprotein CD68, both are members of the lysosomal-associated membrane protein (lamp) family which are located predominantly within the cells and can be detected by flow cytometry using cell permeablisation.Synonyms: Gp110, Macrophage marker, Macrosialin

    基因ID

    12514

    NCBI登录号

    NP_033983

    UniProt

    P31996
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