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IL-2 抗体

IL2 适用: 小鸡, 哺乳动物, Avian EIA, Func 宿主: 小鼠 Monoclonal 4F12 unconjugated
产品编号 ABIN181831
发货至: 中国
  • 抗原 See all IL-2 (IL2) 抗体
    IL-2 (IL2) (Interleukin 2 (IL2))
    适用
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    小鸡, 哺乳动物, Avian
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL-2 antibody is un-conjugated
    应用范围
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    Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody SM1540A recognises natural and recombinant IL-2 expressed in either E.coli or CHO cells. Clone 4F12 neutralises the proliferative activity of rchIL-2 and recognises a different epitope to Clone 10E7 product code (Cat.-No SM1539A). This antibody can be used as the Neutralising antibody for recombinant Chicken IL-2 bioassays (See Product code SA028).
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Recombinant Chicken IL-2. Remarks: Spleen cells from immunised mice were fused with cells of the mouse Sp2/0-Ag myeloma cell line.
    克隆位点
    4F12
    亚型
    IgG2a
    Top Product
    Discover our top product IL2 Primary Antibody
  • 应用备注
    ELISA: 5-10g as capture antibody. Western Blot: Non-reducing conditions. Functional Assays: 2-20g/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS without preservatives, None
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    IL-2 (IL2) (Interleukin 2 (IL2))
    别名
    Interleukin-2 / IL2 (IL2 产品)
    别名
    IL2 antibody, IL-2 antibody, il2 antibody, TCGF antibody, lymphokine antibody, Il-2 antibody, POIL2 antibody, interleukin 2 antibody, interleukin-15 antibody, IL2 antibody, il2 antibody, LOC100303688 antibody, Il2 antibody
    背景
    Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF
    基因ID
    3558
    NCBI登录号
    NP_000577
    UniProt
    P60568
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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