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ITGA6 抗体 (PE)

ITGA6 适用: 人, 小鼠, 犬, Pig, 猴 FACS 宿主: 大鼠 Monoclonal NKI-GoH3 PE
产品编号 ABIN181782
发货至: 中国
  • 抗原 See all ITGA6 抗体
    ITGA6 (Integrin, alpha 6 (ITGA6))
    适用
    • 118
    • 52
    • 25
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    • 15
    • 12
    • 9
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    • 6
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    • 2
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    • 1
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    • 1
    • 1
    人, 小鼠, 犬, Pig, 猴
    宿主
    • 71
    • 38
    • 16
    • 2
    大鼠
    克隆类型
    • 66
    • 59
    单克隆
    标记
    • 70
    • 11
    • 11
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
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    • 2
    • 1
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    This ITGA6 antibody is conjugated to PE
    应用范围
    • 80
    • 49
    • 46
    • 44
    • 23
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    • 13
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    • 13
    • 13
    • 10
    • 3
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises CD49F (VLA-6 alpha chain). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts.VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. We recommend the use of SM038Afor this purpose.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
    克隆位点
    NKI-GoH3
    亚型
    IgG2a
    Top Product
    Discover our top product ITGA6 Primary Antibody
  • 应用备注
    Flow Cytometry: Neat - 1/5, Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.0 mL distilled water.
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ITGA6 (Integrin, alpha 6 (ITGA6))
    别名
    CD49f / ITGA6 (ITGA6 产品)
    别名
    CD49f antibody, ITGA6B antibody, VLA-6 antibody, 5033401O05Rik antibody, AI115430 antibody, Cd49f antibody, ITGA6 antibody, inta6 antibody, im:6897425 antibody, itga6 antibody, si:dkey-32o22.1 antibody, wu:fb80g02 antibody, LOC100221694 antibody, si:dkey-18j14.1 antibody, wu:fl20e08 antibody, zgc:113088 antibody, integrin subunit alpha 6 antibody, integrin alpha 6 antibody, integrin subunit alpha 6 L homeolog antibody, integrin, alpha 6a antibody, integrin, alpha 6b antibody, ITGA6 antibody, Itga6 antibody, itga6.L antibody, itga6a antibody, itga6b antibody
    背景
    CD49F (VLA-6 alpha chain)is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
    基因ID
    3655
    NCBI登录号
    NP_000201
    UniProt
    P23229
    途径
    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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