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ITGA6 抗体 (PE)

This anti-ITGA6 antibody is a 大鼠 单克隆 antibody detecting ITGA6 in FACS. Suitable for 人, 小鼠, 犬, Pig 和 猴.
产品编号 ABIN181782
发货至: 中国

Quick Overview for ITGA6 抗体 (PE) (ABIN181782)

抗原

See all ITGA6 抗体
ITGA6 (Integrin, alpha 6 (ITGA6))

适用

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人, 小鼠, 犬, Pig, 猴

宿主

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大鼠

克隆类型

  • 75
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单克隆

标记

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This ITGA6 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

NKI-GoH3
  • 特异性

    This antibody recognises CD49F (VLA-6 alpha chain). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts.VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. We recommend the use of SM038Afor this purpose.

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: Neat - 1/5, Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1.0 mL distilled water.

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ITGA6 (Integrin, alpha 6 (ITGA6))

    别名

    CD49f / ITGA6

    背景

    CD49F (VLA-6 alpha chain)is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1).Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6

    基因ID

    3655

    NCBI登录号

    NP_000201

    UniProt

    P23229

    途径

    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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