IL-31 抗体
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北京 101111
Quick Overview for IL-31 抗体 (ABIN181696)
抗原
See all IL-31 (IL31) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Human Interleukin-31.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Highly pure (> 98%) E.coli derived recombinant Human IL-31
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anti-Interleukin 31 (IL31) antibody
IL31 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 13-40), (N-Term) antibodyIL31 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22575 unconjugated
anti-Interleukin 31 (IL31) (AA 24-164) antibodyIL31 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 31-130) antibodyIL31 适用: 人 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 21-120) antibodyIL31 适用: 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 28-154) antibodyIL31 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 19-49), (N-Term) antibodyIL31 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) antibodyIL31 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 31 (IL31) (AA 55-183) antibodyIL31 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Interleukin 31 (IL31) (AA 24-164) antibodyIL31 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G9 unconjugated
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应用备注
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ELISA: Indirect: To detect hIL-31 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-31. Sandwich: To detect hIL-31 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with Biotinylated Anti-HumanIL-31 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hIL-31. Western blot: To detect hIL-31 this antibody can be used at a concentration of 0.1 - 0.2g/mL. Used in conjunction with compatible secondary reagents the detection limit forrecombinant hIL-31 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophilized antibody at -20 °C. Following reconstitution the antibody is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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有效期
- 6 months
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- IL-31 (IL31) (Interleukin 31 (IL31))
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别名
- Interleukin-31 / IL31
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背景
- Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia and skin lesions, and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.Synonyms: IL-31
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基因ID
- 386653
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NCBI登录号
- NP_001014358
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UniProt
- Q6EBC2
抗原
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