APOE 抗体 (Isoform E3)
Quick Overview for APOE 抗体 (Isoform E3) (ABIN181668)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Isoform E3
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特异性
- This antibody detects ApoE3. Cross reacts with ApoE2 and ApoE4.
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Highly pure (> 98 %) recombinant human ApoE3
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anti-Apolipoprotein E (APOE) (AA 19-181) antibody
APOE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 19-168) antibodyAPOE 适用: 大鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 1-172) antibodyAPOE 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 19-168) antibodyAPOE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Apolipoprotein E (APOE) (C-Term) antibodyAPOE 适用: 人 WB, ELISA, IP, ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 200-300) antibodyAPOE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) antibodyAPOE 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Apolipoprotein E (APOE) (N-Term) antibodyAPOE 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 151-250) antibodyAPOE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 14-167) antibodyAPOE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: Indirect: To detect hApoE3 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hApoE3. Sandwich: To detect hApoE3 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with Biotinylated Anti-HumanApoE3 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hApoE3. Western blot: To detect hApoE3 this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hApoE3 is 1.5 - 3.0 ng/lane, under either reducing or non-reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1 - 1.0 mg/mL.
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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有效期
- 6 months
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- APOE (Apolipoprotein E (APOE))
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别名
- Apolipoprotein E (Apo E)
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背景
- Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE
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基因ID
- 348
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NCBI登录号
- NP_000032
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UniProt
- P02649
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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