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IL-11 抗体

IL11 适用: 人 WB, EIA, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN181144
发货至: 中国
  • 抗原 See all IL-11 (IL11) 抗体
    IL-11 (IL11) (Interleukin 11 (IL11))
    适用
    • 43
    • 29
    • 28
    宿主
    • 47
    • 15
    • 1
    • 1
    小鼠
    克隆类型
    • 48
    • 16
    单克隆
    标记
    • 30
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    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-11 antibody is un-conjugated
    应用范围
    • 45
    • 31
    • 17
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody detects Human Interleukin-11. Other species not tested.
    产品特性
    Synonyms: IL-11, Adipogenesis inhibitory factor, AGIF
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Highly pure (>98%) recombinant Human IL-11
    亚型
    IgG1
    Top Product
    Discover our top product IL11 Primary Antibody
  • 应用备注
    Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity ofhIL-11 (5.0 ng/mL), a concentration of 2.4-3.6 μg/mL is required. ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 8-9 μg/mL will detectat least 0.2 ng/well of recombinant Human IL-11 when used with Biotin anti-Human IL-11antibody (cat. PP1033B) as the detection antibody at a concentration of at least 2 μg/mL. Western Blot: To detect hIL-11 by Western Blot analysis this antibody can be used at aconcentration of 1.0-2.0 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-11 is 0.25-0.50 ng/lane, under non-reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 1.0 mg/mL.
    缓冲液
    PBS without preservatives
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2 - 8 °C for six weeks. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    IL-11 (IL11) (Interleukin 11 (IL11))
    别名
    Interleukin-11 / IL11 (IL11 产品)
    别名
    IL11 antibody, AGIF antibody, IL-11 antibody, Il-11 antibody, interleukin 11 antibody, IL11 antibody, Il11 antibody
    背景
    Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.Synonyms: AGIF, Adipogenesis inhibitory factor, IL-11
    基因ID
    3589
    UniProt
    P20809
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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