IL-11 抗体
Quick Overview for IL-11 抗体 (ABIN181144)
抗原
See all IL-11 (IL11) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects Human Interleukin-11. Other species not tested.
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产品特性
- Synonyms: IL-11, Adipogenesis inhibitory factor, AGIF
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Highly pure (>98%) recombinant Human IL-11
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亚型
- IgG1
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anti-Interleukin 11 (IL11) (AA 22-199) antibody
IL11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 22-120) antibodyIL11 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 27-61) antibodyIL11 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56890 unconjugated
anti-Interleukin 11 (IL11) antibody (Biotin)IL11 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 11 (IL11) (AA 25-74) antibodyIL11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Interleukin 11 (IL11) (AA 25-199) antibodyIL11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (N-Term) antibodyIL11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity ofhIL-11 (5.0 ng/mL), a concentration of 2.4-3.6 μg/mL is required. ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 8-9 μg/mL will detectat least 0.2 ng/well of recombinant Human IL-11 when used with Biotin anti-Human IL-11antibody (cat. PP1033B) as the detection antibody at a concentration of at least 2 μg/mL. Western Blot: To detect hIL-11 by Western Blot analysis this antibody can be used at aconcentration of 1.0-2.0 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-11 is 0.25-0.50 ng/lane, under non-reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 1.0 mg/mL.
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缓冲液
- PBS without preservatives
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储存液
- Without preservative
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储存条件
- 4 °C/-20 °C
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储存方法
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The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2 - 8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- Interleukin-11 / IL11
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背景
- Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.Synonyms: AGIF, Adipogenesis inhibitory factor, IL-11
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基因ID
- 3589
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UniProt
- P20809
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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