EBV 抗体
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北京 101111
Quick Overview for EBV 抗体 (ABIN181081)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: HHV4, Epstein Barr Virus LMP2A
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Bacterial TrpE-LMP2A fusion protein. Spleen cells from immunised Lou/c rats were fusedwith cells of the P3X63. Ag8. 653 myeloma cell line.
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亚型
- IgG1
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应用备注
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Western Blot: 1/100 - 1/1000. Immunohistochemistry on paraffin sections: This product requires antigen retrieval usingheat treatment methods prior to staining of paraffin sections. Sodium citrate buffer pH 6.0is recommended for this purpose.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- EBV (Epstein-Barr Virus (EBV))
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别名
- Epstein Barr Virus / EBV
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物质类
- Virus
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背景
- EBV is a human herpesvirus, which is associated with conditions such as Hodgkins disease and Burkitts Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.Synonyms: HHV-4, HHV4
抗原
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