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PDCD1LG2 抗体

This anti-PDCD1LG2 antibody is a 大鼠 单克隆 antibody detecting PDCD1LG2 in FACS, IP 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN181078
发货至: 中国

Quick Overview for PDCD1LG2 抗体 (ABIN181078)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

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小鼠

宿主

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大鼠

克隆类型

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  • 2
单克隆

标记

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This PDCD1LG2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

TY25
  • 特异性

    This antiobdy recognises mouse CD273, a 42 kDa member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2).

    产品特性

    Synonyms: PD-L2, PD-1-ligand 2, PDCD1 ligand 2, PDCD1LG2, B7DC, PDCD1L2, Programmed cell death 1ligand 2, Programmed death ligand 2

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    B7-DC transfected RAW264. 7 cells. Lymph node cells from immunised SD rats were fusedwith the cells of the P3U1 myeloma cell line. Genename: CD273

    亚型

    IgG2a
  • 应用备注

    Immunoprecipitation. Immunohistochemistry on frozen sections. Flow Cytometry: 1/100 - 1/200, use 10 μL of the suggested working dilution to label 10^6cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    CD273 / PDL2

    背景

    The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD279). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.Synonyms: B7DC, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2

    基因ID

    58205

    UniProt

    Q9WUL5
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