GM-CSF 抗体
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北京 101111
Quick Overview for GM-CSF 抗体 (ABIN180855)
抗原
See all GM-CSF (CSF2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- When immobilised on a microplate, this antibody will capture recombinant and natural GM-CSF.
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产品特性
- Synonyms: CSF2, GMCSF, Sargramostim, Molgramostin, Granulocyte-macrophage colony-stimulatingfactor, Colony stimulating factor 2
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纯化方法
- Protein A chromatography, 0.2µm sterile filtered
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免疫原
- R-DNA. Genename: GM-CSF
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亚型
- IgG1
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应用备注
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Immunohistochemistry on frozen sections: used at 25g/mLELISA: 1/1K - 1/2K. Western Blot: used at 1-2g/mLFunctional Assays: The neutralisation dose (ND50) of this batch was determined to beapproximately 0.3-0.5 μg/mL in the presence of 0.5 ng/mL of recombinant human GM-CSF. ND50 may vary depending on conditions. ND50 is defined as the concentration of Abrequired to yield half maximal inhibition of cytokine activity on a responsive cell line, whenthat cytokine is present at a concentration just high enough to elicit a maximum response.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2 with 1 % Trehalose
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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别名
- GM-CSF
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背景
- The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim
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基因ID
- 1437
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UniProt
- P04141
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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