FOLR1 抗体
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北京 101111
Quick Overview for FOLR1 抗体 (ABIN180849)
抗原
See all FOLR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Folate Binding Protein (FBP) a 30 kDa protein with a high affinity for folate and several reduced folic acid derivatives, that mediates the intracelullar delivery of 5-Methyl-Tetrahydrofolate. Membrane bound and soluble forms of a high affinity FBP have been found in kidney, placenta, serum, milk, and several cell lines.
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产品特性
- Synonyms: FR-alpha, Folate receptor 1, MOv18, KB cells FBP, FOLR1, FOLR, Adult folate-binding protein,Ovarian tumor-associated antigen MOv18
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Folate binding protein from bovine milk.
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亚型
- IgG1
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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别名
- Folate Receptor alpha
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背景
- Folate Binding Protein, has a high affinity for folic acid and for several reduced folic acid derivatives and mediates delivery of 5 methyltetrahydrofolate to the interior of cells. Membrane bound and soluble forms of a high affinity folate binding protein have been found in kidney, placenta, serum, milk, and in several cell lines. The 2 forms have similar binding characteristics for folates, are immunologically crossreactive, and, based upon limited amino acid sequence data, are nearly identical. There may be a precursor product relationship between the membrane and soluble forms, the membrane form having additional amino acid residues and greater molecular weight. The membrane form has been shown to mediate the transport of folate in cells grown in physiologic concentrations of folate. A function for the soluble form, which is found in serum, milk, and urine, has not been identified.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18
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基因ID
- 2348
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UniProt
- P15328
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途径
- Dicarboxylic Acid Transport
抗原
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