Abeta 38/40/42 (AA 1-16) 抗体
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Quick Overview for Abeta 38/40/42 (AA 1-16) 抗体 (ABIN1742437)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-16
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原理
- Mouse anti-Abeta38/40/42/43 IgG
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特异性
- Specific for Abeta 38, 40, 42.
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交叉反应 (详细)
- Reacts with: human (P05067), mouse (P12023). Other species not tested yet.
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纯化方法
- purified IgG
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免疫原
- Synthetic peptide corresponding to AA 1 to 16 from human Abeta (UniProt Id: P05067) Epitop AA 4 to 16 from human Abeta (UniProt Id: P05067)
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亚型
- IgG2b
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应用备注
- WB:1 : 500 up to 1 : 1000 ,
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说明
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ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.
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缓冲液
- PBS. Azide was added before lyophilization.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,-80 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!
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: "Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in ..." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4454-60, (2011) (PubMed).
: "Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis." in: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41517-24, (2010) (PubMed).
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: "Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in ..." in: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4454-60, (2011) (PubMed).
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- Abeta 38/40/42
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背景
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Synonyms: Beta-APP, ABPP, Abeta, Abeta 38, Abeta 40, Abeta 42, Abeta 43
Antigen Information: Abeta peptides are major components of neuritic plaques in Alzheimer's disease
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UniProt
- P05067
抗原
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