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GFAP 抗体

There are 13+ publications for this product available. The 兔 多克隆 anti-GFAP antibody is suitable to detect GFAP in samples from 人, 大鼠, 小鼠, 小鸡 和 斑马鱼. It has been validated for WB, IHC, ICC, IP 和 IHC (p).
产品编号 ABIN1742363
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GFAP 抗体 (ABIN1742363)

抗原

See all GFAP 抗体
GFAP (Glial Fibrillary Acidic Protein (GFAP))

适用

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宿主

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克隆类型

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多克隆

标记

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This GFAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    Rabbit anti-GFAP antiserum

    特异性

    Specific for GFAP.

    交叉反应 (详细)

    Reacts with: human (P14136), rat (P47819), mouse (P03995), chicken, zebrafish. Other species not tested yet.

    纯化方法

    antiserum

    免疫原

    full-length recombinant human GFAP (UniProt Id: P14136)
  • 应用备注

    WB:1 : 1000 , IP:yes ICC:1 : 1000, IHC:1 : 500, IHC-P:1 : 1000 up to 1 : 5000, ELISA:

    说明

    WB: The polyclonal antibodies are more sensitive compared to the monoclonals. ELISA: Suitable as detector antibody for sandwich-ELISA as capture antibody (protocol for sandwich-ELISA).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
  • Hüttenrauch, Walter, Kaufmann, Weggen, Wirths: "Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice." in: Molecular neurobiology, (2016) (PubMed).

    Hüttenrauch, Baches, Gerth, Bayer, Weggen, Wirths: "Neprilysin deficiency alters the neuropathological and behavioral phenotype in the 5XFAD mouse model of Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 44, Issue 4, pp. 1291-302, (2015) (PubMed).

    Esposito, Drexler, Braganza, Doberentz, Grote, Widman, Drosten, Eis-Hübinger, Schoch, Elger, Becker, Niehusmann: "Large-scale analysis of viral nucleic acid spectrum in temporal lobe epilepsy biopsies." in: Epilepsia, Vol. 56, Issue 2, pp. 234-43, (2015) (PubMed).

    Cavanagh, Colby-Milley, Bouvier, Farso, Chabot, Quirion, Krantic: "βCTF-correlated burst of hippocampal TNFα occurs at a very early, pre-plaque stage in the TgCRND8 mouse model of Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 36, Issue 2, pp. 233-8, (2013) (PubMed).

    Kaeser-Woo, Younts, Yang, Zhou, Wu, Castillo, Südhof: "Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 23, pp. 9769-80, (2013) (PubMed).

    Hillmann, Hahn, Schilling, Hoffmann, Demuth, Bulic, Schneider-Axmann, Bayer, Weggen, Wirths: "No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease." in: Neurobiology of aging, Vol. 33, Issue 4, pp. 833.e39-50, (2012) (PubMed).

    Ansorg, Witte, Urbach: "Age-dependent kinetics of dentate gyrus neurogenesis in the absence of cyclin D2." in: BMC neuroscience, Vol. 13, pp. 46, (2012) (PubMed).

    Araya-Callís, Hiemke, Abumaria, Flugge: "Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus." in: Psychopharmacology, Vol. 224, Issue 1, pp. 209-22, (2012) (PubMed).

    Kawano, Katsurabayashi, Kakazu, Yamashita, Kubo, Kubo, Okuda, Takasaki, Kubota, Mishima, Fujiwara, Harata, Iwasaki: "Long-term culture of astrocytes attenuates the readily releasable pool of synaptic vesicles." in: PLoS ONE, Vol. 7, Issue 10, pp. e48034, (2012) (PubMed).

    Ribic, Flügge, Schlumbohm, Mätz-Rensing, Walter, Fuchs: "Activity-dependent regulation of MHC class I expression in the developing primary visual cortex of the common marmoset monkey." in: Behavioral and brain functions : BBF, Vol. 7, pp. 1, (2011) (PubMed).

    Christensen, Schneider-Axmann, Lucassen, Bayer, Wirths: "Accumulation of intraneuronal Abeta correlates with ApoE4 genotype." in: Acta neuropathologica, Vol. 119, Issue 5, pp. 555-66, (2010) (PubMed).

    Ribic, Zhang, Schlumbohm, Mätz-Rensing, Uchanska-Ziegler, Flügge, Zhang, Walter, Fuchs: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." in: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).

    Wirths, Erck, Martens, Harmeier, Geumann, Jawhar, Kumar, Multhaup, Walter, Ingelsson, Degerman-Gunnarsson, Kalimo, Huitinga, Lannfelt, Bayer: "Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis." in: The Journal of biological chemistry, Vol. 285, Issue 53, pp. 41517-24, (2010) (PubMed).

  • 抗原

    GFAP (Glial Fibrillary Acidic Protein (GFAP))

    别名

    GFAP

    背景

    Synonyms: Glial fibrillary acidic protein, Neuroinflamm-Astrocyt

    Antigen Information: GFAP is an astrocyte-specific type-III intermediate filament protein

    UniProt

    P14136
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