SHANK3 抗体 (C-Term)
Quick Overview for SHANK3 抗体 (C-Term) (ABIN1742347)
抗原
See all SHANK3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Rabbit anti-Shank3 antiserum
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特异性
- Specific for shank 3.
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交叉反应 (详细)
- Reacts with: rat (Q9JLU4), mouse (Q4ACU6). Other species not tested yet.
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纯化方法
- antiserum
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免疫原
- Recombinant protein corresponding to residues near the carboxy terminus of rat Shank3 (UniProt Id: Q9JLU4)
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应用备注
- WB:1 : 1000
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说明
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IHC: For best results the antibody requires a mild fixation protocol (2 % PFA in sodium acetate buffer, pH 6).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
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: "Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses." in: PLoS ONE, Vol. 11, Issue 5, pp. e0153979, (2016) (PubMed).
: "Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder." in: Neurochemical research, Vol. 41, Issue 11, pp. 3129-3137, (2016) (PubMed).
: "Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism." in: Biochimica et biophysica acta, Vol. 1862, Issue 10, pp. 1918-25, (2016) (PubMed).
: "Effects of trace metal profiles characteristic for autism on synapses in cultured neurons." in: Neural plasticity, Vol. 2015, pp. 985083, (2015) (PubMed).
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: "Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses." in: PLoS ONE, Vol. 11, Issue 5, pp. e0153979, (2016) (PubMed).
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- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
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别名
- Shank3
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背景
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Synonyms: SPANK 3, Shanlk-3
Antigen Information: K.O. Shanks are multidomain proteins of the postsynaptic density
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UniProt
- Q9JLU4
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途径
- Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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