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Piccolo 抗体 (AA 4439-4776)

PIC 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1742311
发货至: 中国
  • 抗原 See all Piccolo (PIC) products
    Piccolo (PIC)
    抗原表位
    • 2
    • 1
    • 1
    • 1
    AA 4439-4776
    适用
    • 23
    • 16
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 18
    • 15
    • 1
    • 1
    克隆类型
    • 20
    • 15
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Piccolo antibody is un-conjugated
    应用范围
    • 33
    • 16
    • 15
    • 12
    • 11
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    特异性
    Specific for piccolo.
    纯化方法
    antiserum
    免疫原
    Recombinant rat piccolo (aa 4439-4776).
  • 应用备注
    WB: 1 : 1000 up to 1 : 5000 (ECL detection)
    IP: not tested yet
    ICC: 1 : 200 up to 1 : 500
    说明

    WB: Due to its large size, piccolo requires special gel-electrophoresis and Western blot protocols for visualization by immunoblotting. Excellent results can be obtained with the 4-12% TRIS-glycine gradient gels of anamed. WB: This antibody detects an additional band of ~65 kDa.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS
    注意事项
    Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
    Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.
    储存条件
    4 °C/-20 °C
    储存方法
    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Ribic, Zhang, Schlumbohm, Mätz-Rensing, Uchanska-Ziegler, Flügge, Zhang, Walter, Fuchs: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." in: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).

    Matz, Gilyan, Kolar, McCarvill, Krueger: "Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 19, pp. 8836-41, (2010) (PubMed).

    Szodorai, Kuan, Hunzelmann, Engel, Sakane, Sasaki, Takai, Kirsch, Müller, Beyreuther, Brady, Morfini, Kins: "APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14534-44, (2009) (PubMed).

    Tokoro, Higa, Deguchi-Tawarada, Inoue, Kitajima, Ohtsuka: "Localization of the active zone proteins CAST, ELKS, and Piccolo at neuromuscular junctions." in: Neuroreport, Vol. 18, Issue 4, pp. 313-6, (2007) (PubMed).

    Wahlin, Moreira, Huang, Yu, Adler: "Molecular dynamics of photoreceptor synapse formation in the developing chick retina." in: The Journal of comparative neurology, Vol. 506, Issue 5, pp. 822-37, (2007) (PubMed).

    Dresbach, Torres, Wittenmayer, Altrock, Zamorano, Zuschratter, Nawrotzki, Ziv, Garner, Gundelfinger: "Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment." in: The Journal of biological chemistry, Vol. 281, Issue 9, pp. 6038-47, (2006) (PubMed).

    Juranek, Mukherjee, Rickmann, Martens, Calka, Südhof, Jahn: "Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3043-52, (2006) (PubMed).

    Haeberle, Fujiwara, Chuang, Medina, Panditrao, Bechstedt, Howard, Lumpkin: "Molecular profiling reveals synaptic release machinery in Merkel cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 40, pp. 14503-8, (2004) (PubMed).

  • 抗原
    Piccolo (PIC)
    别名
    Piccolo (PIC 产品)
    背景
    Synonyms: Aczonin
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