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Piccolo 抗体 (AA 4439-4776)

Cited in 8+ publications. This anti-Piccolo antibody is a 兔 多克隆 antibody detecting Piccolo in WB, IHC 和 ICC. Suitable for 大鼠 和 小鼠.
产品编号 ABIN1742311
发货至: 中国
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Quick Overview for Piccolo 抗体 (AA 4439-4776) (ABIN1742311)

抗原

Piccolo (PIC)

适用

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  • 15
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  • 1
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  • 1
  • 1
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  • 1
大鼠, 小鼠

宿主

  • 18
  • 14
  • 1
  • 1

克隆类型

  • 20
  • 14
多克隆

标记

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  • 3
  • 3
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This Piccolo antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

质量等级

KO Validated
  • 抗原表位

    • 3
    • 2
    • 1
    • 1
    • 1
    AA 4439-4776

    原理

    Rabbit anti-Piccolo antiserum

    特异性

    Specific for piccolo.

    交叉反应 (详细)

    Reacts with: rat (Q9JKS6), mouse (Q9QYX7). Other species not tested yet.

    纯化方法

    antiserum

    免疫原

    Recombinant protein corresponding to AA 4439 to 4776 from rat Piccolo (UniProt Id: Q9JKS6)
  • 应用备注

    WB:1 : 1000 up to 1 : 5000 , IP:not tested yet ICC:1 : 500, IHC:1 : 500, IHC-P:not tested yet

    说明

    WB: Due to its large size, piccolo requires special gel-electrophoresis and Western blot protocols for visualization by immunoblotting. Excellent results can be obtained with the 4-12% TRIS-glycine gradient gels of anamed. WB: This antibody detects an additional band of ~65 kDa.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
  • Ribic, Zhang, Schlumbohm, Mätz-Rensing, Uchanska-Ziegler, Flügge, Zhang, Walter, Fuchs: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." in: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).

    Matz, Gilyan, Kolar, McCarvill, Krueger: "Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 19, pp. 8836-41, (2010) (PubMed).

    Szodorai, Kuan, Hunzelmann, Engel, Sakane, Sasaki, Takai, Kirsch, Müller, Beyreuther, Brady, Morfini, Kins: "APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14534-44, (2009) (PubMed).

    Tokoro, Higa, Deguchi-Tawarada, Inoue, Kitajima, Ohtsuka: "Localization of the active zone proteins CAST, ELKS, and Piccolo at neuromuscular junctions." in: Neuroreport, Vol. 18, Issue 4, pp. 313-6, (2007) (PubMed).

    Wahlin, Moreira, Huang, Yu, Adler: "Molecular dynamics of photoreceptor synapse formation in the developing chick retina." in: The Journal of comparative neurology, Vol. 506, Issue 5, pp. 822-37, (2007) (PubMed).

    Dresbach, Torres, Wittenmayer, Altrock, Zamorano, Zuschratter, Nawrotzki, Ziv, Garner, Gundelfinger: "Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment." in: The Journal of biological chemistry, Vol. 281, Issue 9, pp. 6038-47, (2006) (PubMed).

    Juranek, Mukherjee, Rickmann, Martens, Calka, Südhof, Jahn: "Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3043-52, (2006) (PubMed).

    Haeberle, Fujiwara, Chuang, Medina, Panditrao, Bechstedt, Howard, Lumpkin: "Molecular profiling reveals synaptic release machinery in Merkel cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 40, pp. 14503-8, (2004) (PubMed).

  • 抗原

    Piccolo (PIC)

    别名

    Piccolo

    背景

    Synonyms: Aczonin, Pclo, ACZ

    Antigen Information: K.O. Piccolo is a large multi-domain protein of the presynaptic active zone

    UniProt

    Q9JKS6
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