Piccolo 抗体 (AA 4439-4776)
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Quick Overview for Piccolo 抗体 (AA 4439-4776) (ABIN1742311)
抗原
适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 4439-4776
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原理
- Rabbit anti-Piccolo antiserum
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特异性
- Specific for piccolo.
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交叉反应 (详细)
- Reacts with: rat (Q9JKS6), mouse (Q9QYX7). Other species not tested yet.
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纯化方法
- antiserum
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免疫原
- Recombinant protein corresponding to AA 4439 to 4776 from rat Piccolo (UniProt Id: Q9JKS6)
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应用备注
- WB:1 : 1000 up to 1 : 5000 , IP:not tested yet ICC:1 : 500, IHC:1 : 500, IHC-P:not tested yet
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说明
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WB: Due to its large size, piccolo requires special gel-electrophoresis and Western blot protocols for visualization by immunoblotting. Excellent results can be obtained with the 4-12% TRIS-glycine gradient gels of anamed. WB: This antibody detects an additional band of ~65 kDa.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
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: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." in: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).
: "Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 19, pp. 8836-41, (2010) (PubMed).
: "APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 46, pp. 14534-44, (2009) (PubMed).
: "Localization of the active zone proteins CAST, ELKS, and Piccolo at neuromuscular junctions." in: Neuroreport, Vol. 18, Issue 4, pp. 313-6, (2007) (PubMed).
: "Molecular dynamics of photoreceptor synapse formation in the developing chick retina." in: The Journal of comparative neurology, Vol. 506, Issue 5, pp. 822-37, (2007) (PubMed).
: "Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment." in: The Journal of biological chemistry, Vol. 281, Issue 9, pp. 6038-47, (2006) (PubMed).
: "Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3043-52, (2006) (PubMed).
: "Molecular profiling reveals synaptic release machinery in Merkel cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 40, pp. 14503-8, (2004) (PubMed).
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: "Neuronal MHC class I molecules are involved in excitatory synaptic transmission at the hippocampal mossy fiber synapses of marmoset monkeys." in: Cellular and molecular neurobiology, Vol. 30, Issue 6, pp. 827-39, (2010) (PubMed).
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- Piccolo (PIC)
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别名
- Piccolo
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背景
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Synonyms: Aczonin, Pclo, ACZ
Antigen Information: K.O. Piccolo is a large multi-domain protein of the presynaptic active zone
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UniProt
- Q9JKS6
抗原
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