RIMS2 抗体 (AA 461-987)
Quick Overview for RIMS2 抗体 (AA 461-987) (ABIN1742308)
抗原
See all RIMS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 461-987
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原理
- anti-RIM2
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特异性
- RIM 2 including splice variants
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交叉反应 (详细)
- Reacts with: rat (Q9JIS1), mouse (Q9EQZ7), hamster, chicken, zebrafish. Other species not tested yet.
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纯化方法
- affinity purified
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免疫原
- Recombinant protein corresponding to AA 461 to 987 from rat Rim2 (UniProt Id: Q9JIS1)
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应用备注
- WB:1 : 100 up to 1 : 1000 , IHC-P:1 : 500,
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说明
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This antibody works with paraformaldehyde and methanol fixation.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.
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缓冲液
- PBS. Albumin and azide were added for stabilization.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,-80 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
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: "Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse." in: The EMBO journal, Vol. 33, Issue 5, pp. 512-27, (2014) (PubMed).
: "Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina." in: Molecular vision, Vol. 20, pp. 1422-33, (2014) (PubMed).
: "Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain." in: Biology open, Vol. 2, Issue 5, pp. 492-8, (2013) (PubMed).
: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).
: "Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule." in: Molecular and cellular neurosciences, Vol. 44, Issue 3, pp. 246-59, (2010) (PubMed).
: "Molecular anatomy of the hair cell's ribbon synapse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 37, pp. 12387-99, (2010) (PubMed).
: "Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres." in: The Journal of comparative neurology, Vol. 512, Issue 6, pp. 814-24, (2008) (PubMed).
: "Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells." in: Diabetes, Vol. 56, Issue 10, pp. 2579-88, (2007) (PubMed).
: "A proteomic screen for presynaptic terminal N-type calcium channel (CaV2.2) binding partners." in: Journal of biochemistry and molecular biology, Vol. 40, Issue 3, pp. 302-14, (2007) (PubMed).
: "ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca2+-dependent exocytosis from PC12 cells." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 6, pp. 659-72, (2006) (PubMed).
: "Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3043-52, (2006) (PubMed).
: "Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 825-36, (2005) (PubMed).
: "ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic beta cells and functions in insulin exocytosis: interaction of ELKS with exocytotic ..." in: Molecular biology of the cell, Vol. 16, Issue 7, pp. 3289-300, (2005) (PubMed).
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: "Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse." in: The EMBO journal, Vol. 33, Issue 5, pp. 512-27, (2014) (PubMed).
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- RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
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别名
- RIM2
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背景
- Active Zone, CAZ
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UniProt
- Q9JIS1
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途径
- Hormone Transport, Synaptic Vesicle Exocytosis
抗原
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