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RIMS2 抗体 (AA 461-987)

Cited in 13+ publications. This 兔 多克隆 anti-RIMS2 antibody specifically detects RIMS2 in WB, IHC (p) 和 ICC. The antibody is reactive with 大鼠, 小鼠, 小鸡, Hamster 和 斑马鱼 samples.
产品编号 ABIN1742308
发货至: 中国
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Quick Overview for RIMS2 抗体 (AA 461-987) (ABIN1742308)

抗原

See all RIMS2 抗体
RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

适用

大鼠, 小鼠, 小鸡, Hamster, 斑马鱼

宿主

  • 26
  • 10
  • 1

克隆类型

  • 29
  • 8
多克隆

标记

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This RIMS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 抗原表位

    • 5
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    AA 461-987

    原理

    anti-RIM2

    特异性

    RIM 2 including splice variants

    交叉反应 (详细)

    Reacts with: rat (Q9JIS1), mouse (Q9EQZ7), hamster, chicken, zebrafish. Other species not tested yet.

    纯化方法

    affinity purified

    免疫原

    Recombinant protein corresponding to AA 461 to 987 from rat Rim2 (UniProt Id: Q9JIS1)
  • 应用备注

    WB:1 : 100 up to 1 : 1000 , IHC-P:1 : 500,

    说明

    This antibody works with paraformaldehyde and methanol fixation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

    缓冲液

    PBS. Albumin and azide were added for stabilization.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,-80 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
  • Mendoza Schulz, Jing, Sánchez Caro, Wetzel, Dresbach, Strenzke, Wichmann, Moser: "Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse." in: The EMBO journal, Vol. 33, Issue 5, pp. 512-27, (2014) (PubMed).

    de Andrade, Kunzelman, Merrill, Fuerst: "Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina." in: Molecular vision, Vol. 20, pp. 1422-33, (2014) (PubMed).

    Gardezi, Li, Stanley: "Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain." in: Biology open, Vol. 2, Issue 5, pp. 492-8, (2013) (PubMed).

    Limbach, Laue, Wang, Hu, Thiede, Hultqvist, Kilimann: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).

    Gebhart, Juhasz-Vedres, Zuccotti, Brandt, Engel, Trockenbacher, Kaur, Obermair, Knipper, Koschak, Striessnig: "Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule." in: Molecular and cellular neurosciences, Vol. 44, Issue 3, pp. 246-59, (2010) (PubMed).

    Uthaiah, Hudspeth: "Molecular anatomy of the hair cell's ribbon synapse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 37, pp. 12387-99, (2010) (PubMed).

    Regus-Leidig, Tom Dieck, Specht, Meyer, Brandstätter: "Early steps in the assembly of photoreceptor ribbon synapses in the mouse retina: the involvement of precursor spheres." in: The Journal of comparative neurology, Vol. 512, Issue 6, pp. 814-24, (2008) (PubMed).

    Kwan, Xie, Sheu, Ohtsuka, Gaisano: "Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells." in: Diabetes, Vol. 56, Issue 10, pp. 2579-88, (2007) (PubMed).

    Khanna, Zougman, Stanley: "A proteomic screen for presynaptic terminal N-type calcium channel (CaV2.2) binding partners." in: Journal of biochemistry and molecular biology, Vol. 40, Issue 3, pp. 302-14, (2007) (PubMed).

    Inoue, Deguchi-Tawarada, Takao-Rikitsu, Inoue, Kitajima, Ohtsuka, Takai: "ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca2+-dependent exocytosis from PC12 cells." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 6, pp. 659-72, (2006) (PubMed).

    Juranek, Mukherjee, Rickmann, Martens, Calka, Südhof, Jahn: "Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification." in: The European journal of neuroscience, Vol. 24, Issue 11, pp. 3043-52, (2006) (PubMed).

    tom Dieck, Altrock, Kessels, Qualmann, Regus, Brauner, Fejtová, Bracko, Gundelfinger, Brandstätter: "Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 825-36, (2005) (PubMed).

    Ohara-Imaizumi, Ohtsuka, Matsushima, Akimoto, Nishiwaki, Nakamichi, Kikuta, Nagai, Kawakami, Watanabe, Nagamatsu et al.: "ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic beta cells and functions in insulin exocytosis: interaction of ELKS with exocytotic ..." in: Molecular biology of the cell, Vol. 16, Issue 7, pp. 3289-300, (2005) (PubMed).

  • 抗原

    RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

    别名

    RIM2

    背景

    Active Zone, CAZ

    UniProt

    Q9JIS1

    途径

    Hormone Transport, Synaptic Vesicle Exocytosis
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