Rab-GDI 1 (AA 1-447) 抗体
This 小鼠 单克隆 antibody specifically detects Rab-GDI 1 in IP 和 WB. It exhibits reactivity toward Cow, Hamster, 人, 小鼠 和 大鼠. It has been mentioned in 17+ publications
1 image
(17 references)
产品编号 ABIN1742290
发货至:
中国
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Quick Overview for Rab-GDI 1 (AA 1-447) 抗体 (ABIN1742290)
抗原
Rab-GDI 1
适用
Cow, Hamster, 人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
应用范围
Immunoprecipitation (IP), Western Blotting (WB)
克隆位点
81-2
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抗原表位
- AA 1-447
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原理
- Mouse anti-Rab-GDI1 IgG
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特异性
- Recognizes Rab-GDI-alpha and -beta.
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交叉反应 （详细）
- Reacts with: human (P31150), rat (P50398), mouse (P50396), hamster, cow. Other species not tested yet.
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纯化方法
- purified IgG
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免疫原
- Recombinant protein corresponding to AA 1 to 447 from bovine Rab-GDI1 (UniProt Id: P21856)
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亚型
- IgG1
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应用备注
- WB:1 : 1000 up to 1 : 10000 ICC:not tested yet IHC:not recommended IHC-P:not tested yet
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说明
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Immunoprecipitates Rab-GDI complexes.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.
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缓冲液
- PBS. Albumin and azide were added for stabilization.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,-80 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
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: "Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis." in: Oncogene, Vol. 36, Issue 41, pp. 5757-5767, (2017) (PubMed).
: "The GTPase Rab26 links synaptic vesicles to the autophagy pathway." in: eLife, Vol. 4, pp. e05597, (2015) (PubMed).
: "Ear2 deletion causes early memory and learning deficits in APP/PS1 mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 26, pp. 8845-54, (2014) (PubMed).
: "α-Synuclein membrane association is regulated by the Rab3a recycling machinery and presynaptic activity." in: The Journal of biological chemistry, Vol. 288, Issue 11, pp. 7438-49, (2013) (PubMed).
: "Mover is a homomeric phospho-protein present on synaptic vesicles." in: PLoS ONE, Vol. 8, Issue 5, pp. e63474, (2013) (PubMed).
: "RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction." in: Cell, Vol. 144, Issue 2, pp. 282-95, (2011) (PubMed).
: "Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro." in: Science (New York, N.Y.), Vol. 329, Issue 5999, pp. 1663-7, (2010) (PubMed).
: "Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 40, pp. 13441-53, (2010) (PubMed).
: "Endosomal sorting of readily releasable synaptic vesicles." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 19055-60, (2010) (PubMed).
: "CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity." in: Nature cell biology, Vol. 13, Issue 1, pp. 30-9, (2010) (PubMed).
: "SynCAMs organize synapses through heterophilic adhesion." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 46, pp. 12516-30, (2007) (PubMed).
: "A dual function for Munc-18 in exocytosis of PC12 cells." in: The European journal of neuroscience, Vol. 21, Issue 9, pp. 2419-32, (2005) (PubMed).
: "Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term ..." in: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12286-92, (2004) (PubMed).
: "Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules." in: Molecular and cellular biology, Vol. 22, Issue 18, pp. 6487-97, (2002) (PubMed).
: "Binding of Rab3A to synaptic vesicles." in: The Journal of biological chemistry, Vol. 275, Issue 13, pp. 9433-40, (2000) (PubMed).
: "Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses." in: The European journal of neuroscience, Vol. 11, Issue 4, pp. 1335-48, (1999) (PubMed).
: "Rabphilin knock-out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 14, pp. 5834-46, (1999) (PubMed).
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- Rab-GDI 1
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别名
- Rab-GDI1
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背景
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Synonyms: GDI 1, Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, SMG p25A GDI
Antigen Information: The cytoplasmatic protein Rab-GDI binds to GDP-Rabs
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UniProt
- P21856
抗原
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