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Neuroligin (NEUROLIGIN) (AA 1-695) 抗体

There are 6+ publications for this product available. The 小鼠 单克隆 anti-Neuroligin antibody is suitable to detect Neuroligin in samples from 小鼠 和 大鼠. It has been validated for IP 和 WB.
产品编号 ABIN1742285
发货至: 中国
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Quick Overview for Neuroligin (NEUROLIGIN) (AA 1-695) 抗体 (ABIN1742285)

抗原

Neuroligin (NEUROLIGIN)

适用

小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

应用范围

Immunoprecipitation (IP), Western Blotting (WB)

质量等级

KO Validated

克隆位点

4F9
  • 抗原表位

    AA 1-695

    原理

    Mouse anti-Neuroligin1/2/3/4 IgG

    特异性

    Recognizes rat and mouse neuroligins 1-3 and rat neuroligin 4.

    交叉反应 (详细)

    Reacts with: rat (Q62765, Q62888, Q62889, ), mouse (Q99K10, Q69ZK9, Q8BYM5, B0F2B4). Other species not tested yet.

    纯化方法

    purified IgG

    免疫原

    Recombinant protein corresponding to AA 1 to 695 from rat Neuroligin1 (UniProt Id: Q62765)

    亚型

    IgG2a
  • 应用备注

    WB:1 : 1000 , IP:yes ICC:not recommended IHC:not recommended IHC-P:not tested yet

    说明

    ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

    缓冲液

    PBS. Albumin and azide were added for stabilization.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,-80 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!
  • Jadhav, Katina, Kovac, Kazmerova, Novak, Zilka: "Truncated tau deregulates synaptic markers in rat model for human tauopathy." in: Frontiers in cellular neuroscience, Vol. 9, pp. 24, (2015) (PubMed).

    Fujita-Jimbo, Tanabe, Yu, Kojima, Mori, Li, Iwamoto, Yamagata, Momoi, Momoi: "The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis." in: Molecular autism, Vol. 6, pp. 17, (2015) (PubMed).

    Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." in: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

    Bottos, Destro, Rissone, Graziano, Cordara, Assenzio, Cera, Mascia, Bussolino, Arese: "The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20782-7, (2010) (PubMed).

    De Jaco, Comoletti, Kovarik, Gaietta, Radic, Lockridge, Ellisman, Taylor: "A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9667-76, (2006) (PubMed).

    Chih, Engelman, Scheiffele: "Control of excitatory and inhibitory synapse formation by neuroligins." in: Science (New York, N.Y.), Vol. 307, Issue 5713, pp. 1324-8, (2005) (PubMed).

  • 抗原

    Neuroligin (NEUROLIGIN)

    别名

    Neuroligin

    背景

    Synonyms: Neuroligin1, Neuroligin2, Neuroligin3, Synaptic Adhesion Proteins, Neuroligin 1, Neuroligin 2, Neuroligin 3, Neuroligin 4, Neuroligin4

    Antigen Information: K.O. Neuroligins are postsynaptic cell adhesion molecules

    UniProt

    Q62765
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