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Neuroligin 1/2/3/4 抗体 (AA 1-695)

This anti-Neuroligin 1/2/3/4 antibody is a 小鼠 单克隆 antibody detecting Neuroligin 1/2/3/4 in IP, ELISA 和 WB. Suitable for 小鼠 和 大鼠. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN1742285
发货至: 中国

Quick Overview for Neuroligin 1/2/3/4 抗体 (AA 1-695) (ABIN1742285)

抗原

Neuroligin 1/2/3/4 (NLGN1/2/3/4)

适用

小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

应用范围

Immunoprecipitation (IP), ELISA, Western Blotting (WB)

克隆位点

4F9
  • 抗原表位

    AA 1-695

    特异性

    Recognizes rat and mouse neuroligins 1-3 and rat neuroligin 4.

    纯化方法

    purified IgG

    免疫原

    Recombinant protein of rat neuroligin 1 containing the extracellular sequence (aa 1-695).

    亚型

    IgG2a
  • 应用备注

    WB: 1 : 1000 (AP staining)
    ICC: not recommended
    IHC: not recommended

    说明

    ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

    缓冲液

    PBS

    注意事项

    Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.

    储存条件

    -20 °C

    储存方法

    Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
  • Jadhav, Katina, Kovac, Kazmerova, Novak, Zilka: "Truncated tau deregulates synaptic markers in rat model for human tauopathy." in: Frontiers in cellular neuroscience, Vol. 9, pp. 24, (2015) (PubMed).

    Fujita-Jimbo, Tanabe, Yu, Kojima, Mori, Li, Iwamoto, Yamagata, Momoi, Momoi: "The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis." in: Molecular autism, Vol. 6, pp. 17, (2015) (PubMed).

    Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." in: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

    Bottos, Destro, Rissone, Graziano, Cordara, Assenzio, Cera, Mascia, Bussolino, Arese: "The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20782-7, (2010) (PubMed).

    De Jaco, Comoletti, Kovarik, Gaietta, Radic, Lockridge, Ellisman, Taylor: "A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9667-76, (2006) (PubMed).

    Chih, Engelman, Scheiffele: "Control of excitatory and inhibitory synapse formation by neuroligins." in: Science (New York, N.Y.), Vol. 307, Issue 5713, pp. 1324-8, (2005) (PubMed).

  • 抗原

    Neuroligin 1/2/3/4 (NLGN1/2/3/4)

    别名

    Neuroligin
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