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Alpha, beta Synuclein (AA 2-25), (N-Term) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB, ICC, IHC 和 IP. Suitable for 小鼠, 大鼠 和 斑马鱼. This Primary Antibody has been cited in 7+ publications.
产品编号 ABIN1742282
发货至: 中国

Quick Overview for Alpha, beta Synuclein (AA 2-25), (N-Term) 抗体 (ABIN1742282)

抗原

Alpha, beta Synuclein

适用

小鼠, 大鼠, 斑马鱼

宿主

  • 7
  • 3

克隆类型

  • 10
多克隆

标记

  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

    AA 2-25, N-Term

    特异性

    Recognizes alpha synuclein and beta synuclein.

    免疫原

    Synthetic peptide DVFMKGLSKAKEGVVAAAEKTKQG (aa 2-25 in alpha synuclein), coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
  • 应用备注

    WB: 1:1000, ICC: 1:500, IHC: 1:500,

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200µl H2O.

    储存液

    Azide and BSA free

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    4 °C/-20 °C

    储存方法

    Reconstitute and aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized.
  • Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

    Siebert, Kahle, Kramer, Isik, Schlüter, Schulz-Schaeffer, Brück: "Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain." in: Journal of neurochemistry, Vol. 114, Issue 4, pp. 1007-18, (2010) (PubMed).

    Tong, Wong, Guttman, Ang, Forno, Shimadzu, Rajput, Muenter, Kish, Hornykiewicz, Furukawa: "Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation." in: Brain : a journal of neurology, Vol. 133, Issue Pt 1, pp. 172-88, (2010) (PubMed).

    Cole, Dieuliis, Leo, Mitchell, Nussbaum: "Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification." in: Experimental cell research, Vol. 314, Issue 10, pp. 2076-89, (2008) (PubMed).

    Colapinto, Mila, Giraudo, Stefanazzi, Molteni, Rossetti, Bergamasco, Lopiano, Fasano: "alpha-Synuclein protects SH-SY5Y cells from dopamine toxicity." in: Biochemical and biophysical research communications, Vol. 349, Issue 4, pp. 1294-300, (2006) (PubMed).

    Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

    Steinacker, Schwarz, Reim, Brechlin, Jahn, Kratzin, Aitken, Wiltfang, Aguzzi, Bahn, Baxter, Brose, Otto: "Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1339-46, (2005) (PubMed).

  • 抗原

    Alpha, beta Synuclein

    别名

    alpha/beta Synuclein

    背景

    Synonyms: alpha-Synuclein, beta-Synuclein
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