Alpha, beta Synuclein (AA 2-25) 抗体
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北京 101111
Quick Overview for Alpha, beta Synuclein (AA 2-25) 抗体 (ABIN1742282)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-25
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原理
- Rabbit anti-alpha/beta Synuclein antiserum
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特异性
- Recognizes alpha synuclein and beta synuclein.
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交叉反应 （详细）
- Reacts with: rat (P37377, Q63754), mouse (O55042, Q91ZZ3), zebrafish, human (P37840, Q16143). Other species not tested yet.
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纯化方法
- antiserum
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免疫原
- Synthetic peptide corresponding to AA 2 to 25 from human alpha-Synuclein (UniProt Id: P37840)
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anti-Alpha, beta Synuclein antibody
适用: 人, 小鼠 WB, IF, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-Alpha, beta Synuclein (AA 1-140) antibody适用: 人, 小鼠, 大鼠 ICC, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 56F2 unconjugated
anti-Alpha, beta Synuclein (AA 119-140) antibody适用: 人 WB, ICC, IF, FACS, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
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应用备注
- WB:1 : 1000 , IP:yes ICC:1 : 500, IHC:1 : 500, IHC-P:1 : 1000 up to 1 : 2000,
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
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: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).
: "Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain." in: Journal of neurochemistry, Vol. 114, Issue 4, pp. 1007-18, (2010) (PubMed).
: "Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation." in: Brain : a journal of neurology, Vol. 133, Issue Pt 1, pp. 172-88, (2010) (PubMed).
: "Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification." in: Experimental cell research, Vol. 314, Issue 10, pp. 2076-89, (2008) (PubMed).
: "alpha-Synuclein protects SH-SY5Y cells from dopamine toxicity." in: Biochemical and biophysical research communications, Vol. 349, Issue 4, pp. 1294-300, (2006) (PubMed).
: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).
: "Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein." in: Molecular and cellular biology, Vol. 25, Issue 4, pp. 1339-46, (2005) (PubMed).
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: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).
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- Alpha, beta Synuclein
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别名
- alpha/beta Synuclein
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背景
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Synonyms: alpha/beta Synuclein, SNCA, SNCB, NACP, Synuclein
Antigen Information: Synucleins are involved in Parkinson's and Alzheimer's Disease
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UniProt
- P37840
抗原
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