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UNC13A/Munc13-1 抗体 (AA 3-317)

Cited in 3+ publications. The 兔 多克隆 anti-UNC13A/Munc13-1 antibody (ABIN1742277) specifically detects UNC13A/Munc13-1 in WB, ICC, IP 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠 和 斑马鱼 samples.
产品编号 ABIN1742277
发货至: 中国
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Quick Overview for UNC13A/Munc13-1 抗体 (AA 3-317) (ABIN1742277)

抗原

See all UNC13A/Munc13-1 (UNC13A) 抗体
UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

适用

  • 7
  • 4
  • 3
  • 2
  • 1
人, 小鼠, 大鼠, 斑马鱼

宿主

  • 5
  • 2
  • 1
  • 1

克隆类型

  • 8
  • 1
多克隆

标记

  • 9
This UNC13A/Munc13-1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC)

质量等级

KO Validated
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    AA 3-317

    原理

    Rabbit anti-Munc13-1 antiserum

    特异性

    Specific for munc 13-1.

    交叉反应 (详细)

    Reacts with: human (Q9UPW8), rat (Q62768), mouse (Q4KUS2), zebrafish. Other species not tested yet.

    纯化方法

    antiserum

    免疫原

    Recombinant protein corresponding to AA 3 to 317 from rat Munc13-1 (UniProt Id: Q62768)
  • 应用备注

    WB:1 : 1000 , IP:yes ICC:1 : 500, IHC:1 : 200, IHC-P:not tested yet

    说明

    IP: For most effective IP use the solubilization protocol described in the ELISA protocol. Consider that protein-protein interaction may be affected. ICC: This antibody gives much better results in ICC than the monoclonal antibody. ELISA: Suitable as detector antibody for sandwich-ELISA with ABIN1742276 as capture antibody (protocol for sandwich-ELISA).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
  • Fernandes, Riordan, Nomura, Remmers, Kraniotis, Marshall, Kukreja, Vassar, Contractor: "Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6544-53, (2015) (PubMed).

    Juranek, Mukherjee, Siddiqui, Kaplan, Li, Ahnert-Hilger, Jahn, Calka: "Active zone protein expression changes at the key stages of cerebellar cortex neurogenesis in the rat." in: Acta histochemica, Vol. 115, Issue 6, pp. 616-25, (2013) (PubMed).

    Rinetti, Schweizer: "Ubiquitination acutely regulates presynaptic neurotransmitter release in mammalian neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 9, pp. 3157-66, (2010) (PubMed).

  • 抗原

    UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

    别名

    Munc13-1

    背景

    Synonyms: Munc13-1, Munc13, Protein unc-13 homolog A, Unc13a, Unc13h1, Brain, Hippocampus, Cerebellum, Olfactory bulb, Cortex, Striatum

    Antigen Information: K.O. Munc13 proteins are the mammalian homologues of the C. elegans unc-13 gene essential for exocytosis

    UniProt

    Q62768

    途径

    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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