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Complexin 1, 2 (AA 45-81) 抗体

Cited in 5+ publications. The 兔 多克隆 anti-Complexin 1, 2 antibody (ABIN1742265) specifically detects Complexin 1, 2 in ICC, IHC, IHC (p), IP 和 WB. The antibody is reactive with 小鼠, 大鼠, 人, Cow, 豚鼠, 兔 和 斑马鱼 samples.
产品编号 ABIN1742265
发货至: 中国
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Quick Overview for Complexin 1, 2 (AA 45-81) 抗体 (ABIN1742265)

抗原

Complexin 1, 2

适用

小鼠, 大鼠, 人, Cow, 豚鼠, 兔, 斑马鱼

宿主

  • 1
  • 1

克隆类型

  • 1
  • 1
多克隆

标记

  • 2
非结合性

应用范围

Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

质量等级

KO Validated
  • 抗原表位

    • 1
    • 1
    AA 45-81

    原理

    anti-Complexin1/2

    特异性

    Recognizes complexin 1 and 2.

    交叉反应 (详细)

    Reacts with: human (O14810, Q6PUV4), rat (P63041, P84087), mouse (P63040, P84086), Guinea pig, cow, zebrafish, rabbit. Other species not tested yet.

    纯化方法

    antiserum

    免疫原

    Synthetic peptide corresponding to AA 45 to 81 from mouse Complexin2 (UniProt Id: P84086)
  • 应用备注

    WB:1 : 1000 up to 1 : 20000 ICC:1 : 200 up to 1 : 500, IHC:1 : 500, IHC-P:1 : 200,

    说明

    IP: Co-immunoprecipitates the SNARE complex.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
  • Getz, Visser, Bell, Xu, Flynn, Zaidi, Syed: "Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons." in: Scientific reports, Vol. 6, pp. 31779, (2016) (PubMed).

    Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

    Tsai, Brewis, van Maaren, Gadella: "Involvement of complexin 2 in docking, locking and unlocking of different SNARE complexes during sperm capacitation and induced acrosomal exocytosis." in: PLoS ONE, Vol. 7, Issue 3, pp. e32603, (2012) (PubMed).

    Lee, Brecha: "Immunocytochemical evidence for SNARE protein-dependent transmitter release from guinea pig horizontal cells." in: The European journal of neuroscience, Vol. 31, Issue 8, pp. 1388-401, (2010) (PubMed).

    Falkowski, Thomas, Groblewski: "Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini." in: The Journal of biological chemistry, Vol. 285, Issue 46, pp. 35558-66, (2010) (PubMed).

  • 抗原

    Complexin 1, 2

    别名

    Complexin 1/2

    背景

    CPX 1, CPX1, CPX 2, CPX2, Synaphin-1, complexin 1, complexin 2, SNARE associated, eye-retina, 2

    UniProt

    P84086
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