SV2B 抗体 (AA 2-17)
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北京 101111
Quick Overview for SV2B 抗体 (AA 2-17) (ABIN1742258)
抗原
See all SV2B 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 2-17
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原理
- Rabbit anti-SV2 B antiserum
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特异性
- Specific for SV2 B.
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交叉反应 （详细）
- Reacts with: human (Q7L1I2), rat (Q63564), mouse (Q8BG39), hamster, chicken. Other species not tested yet.
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纯化方法
- antiserum
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免疫原
- Synthetic peptide corresponding to AA 2 to 17 from rat SV2B (UniProt Id: Q63564)
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anti-Synaptic Vesicle Glycoprotein 2B (SV2B) (AA 2-17) antibody
SV2B 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), ICC, IP 宿主: 小鼠 Monoclonal 246E8 unconjugated
anti-Synaptic Vesicle Glycoprotein 2B (SV2B) (AA 2-17) antibodySV2B 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), ICC, IP 宿主: 豚鼠 Polyclonal unconjugated
anti-Synaptic Vesicle Glycoprotein 2B (SV2B) (AA 1-108) antibodySV2B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptic Vesicle Glycoprotein 2B (SV2B) (AA 417-476) antibodySV2B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Synaptic Vesicle Glycoprotein 2B (SV2B) (AA 1-683) antibodySV2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptic Vesicle Glycoprotein 2B (SV2B) (AA 1-683) antibodySV2B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB:1 : 1000
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说明
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WB: SV2 aggregates after boiling, making it necessary to run SDS-PAGE only with non-boiled samples.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.
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注意事项
- Do not freeze! Antibodies should be stored at +4°C when still lyophilized.
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储存条件
- -20 °C,4 °C
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储存方法
- Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
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: "SV2B is essential for the integrity of the glomerular filtration barrier." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 5, pp. 534-45, (2015) (PubMed).
: "Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis." in: Neuropathology and applied neurobiology, Vol. 40, Issue 2, pp. 191-204, (2014) (PubMed).
: "Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting." in: The EMBO journal, Vol. 33, Issue 2, pp. 157-70, (2014) (PubMed).
: "Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E." in: The Biochemical journal, Vol. 453, Issue 1, pp. 37-47, (2013) (PubMed).
: "Expression of SV2 isoforms during rodent brain development." in: BMC neuroscience, Vol. 14, pp. 87, (2013) (PubMed).
: "Preferential entry of botulinum neurotoxin A Hc domain through intestinal crypt cells and targeting to cholinergic neurons of the mouse intestine." in: PLoS pathogens, Vol. 8, Issue 3, pp. e1002583, (2012) (PubMed).
: "Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10189-200, (2011) (PubMed).
: "Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam." in: Neuroscience, Vol. 171, Issue 1, pp. 268-83, (2010) (PubMed).
: "SV2 mediates entry of tetanus neurotoxin into central neurons." in: PLoS pathogens, Vol. 6, Issue 11, pp. e1001207, (2010) (PubMed).
: "Loss of the Synaptic Vesicle Protein SV2B results in reduced neurotransmission and altered synaptic vesicle protein expression in the retina." in: PLoS ONE, Vol. 4, Issue 4, pp. e5230, (2009) (PubMed).
: "Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers." in: Cellular microbiology, Vol. 10, Issue 2, pp. 375-87, (2008) (PubMed).
: "Traffic of botulinum toxins A and E in excitatory and inhibitory neurons." in: Traffic (Copenhagen, Denmark), Vol. 8, Issue 2, pp. 142-53, (2007) (PubMed).
: "Synaptic vesicle protein 2B is expressed in podocyte, and its expression is altered in proteinuric glomeruli." in: Journal of the American Society of Nephrology : JASN, Vol. 17, Issue 10, pp. 2748-59, (2006) (PubMed).
: "SV2A and SV2C contain a unique synaptotagmin-binding site." in: Molecular and cellular neurosciences, Vol. 29, Issue 1, pp. 56-64, (2005) (PubMed).
: "The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina." in: Cell and tissue research, Vol. 311, Issue 2, pp. 159-73, (2003) (PubMed).
: "Brain synaptic junctional proteins at the acrosome of rat testicular germ cells." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 51, Issue 6, pp. 809-19, (2003) (PubMed).
: "SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family." in: Neuroscience, Vol. 94, Issue 4, pp. 1279-90, (2000) (PubMed).
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: "SV2B is essential for the integrity of the glomerular filtration barrier." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 5, pp. 534-45, (2015) (PubMed).
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- SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))
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别名
- SV2 B
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背景
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Synonyms: synaptic vesicle protein 2B, SV2, SV2-B, synaptic vesicle protein 2
Antigen Information: K.O. SV2s are highly glycosylated synaptic vesicle proteins with homology to transmembrane transporters
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UniProt
- Q63564
抗原
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