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Dynamin 1, 2, 3 (AA 2-17) 抗体

This 兔 多克隆 antibody specifically detects Dynamin 1, 2, 3 in ICC, IHC, IHC (p), IP 和 WB. It exhibits reactivity toward Cow, 人, 小鼠 和 大鼠. It has been mentioned in 7+ publications
产品编号 ABIN1742248
发货至: 中国
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Quick Overview for Dynamin 1, 2, 3 (AA 2-17) 抗体 (ABIN1742248)

抗原

Dynamin 1, 2, 3

适用

Cow, 人, 小鼠, 大鼠

宿主

克隆类型

多克隆

应用范围

Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

质量等级

KD Validated
  • 抗原表位

    AA 2-17

    原理

    Rabbit anti-Dynamin1/2/3 antiserum

    特异性

    Recognizes dynamin 1, 2 and 3 with a preference for dynamin 1.

    交叉反应 (详细)

    Reacts with: human (Q05193, P50570, Q9UQ16), rat (P21575, P39052, Q08877), mouse (P39053, P39054, Q8BZ98), cow. Other species not tested yet.

    纯化方法

    antiserum

    免疫原

    Synthetic peptide corresponding to AA 2 to 17 from rat Dynamin1 (UniProt Id: P21575)
  • 应用备注

    WB:1 : 1000 , IP:yes ICC:1 : 200 up to 1 : 1000, IHC:1 : 500, IHC-P:1 : 100,

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

    注意事项

    Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

    储存条件

    -20 °C,4 °C

    储存方法

    Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
  • Biesemann, Grønborg, Luquet, Wichert, Bernard, Bungers, Cooper, Varoqueaux, Li, Byrne, Urlaub, Jahn, Brose, Herzog: "Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting." in: The EMBO journal, Vol. 33, Issue 2, pp. 157-70, (2014) (PubMed).

    Wilhelm, Mandad, Truckenbrodt, Kröhnert, Schäfer, Rammner, Koo, Claßen, Krauss, Haucke, Urlaub, Rizzoli: "Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins." in: Science (New York, N.Y.), Vol. 344, Issue 6187, pp. 1023-8, (2014) (PubMed).

    Rozas, Gómez-Sánchez, Tomás-Zapico, Lucas, Fernández-Chacón: "Increased neurotransmitter release at the neuromuscular junction in a mouse model of polyglutamine disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 3, pp. 1106-13, (2011) (PubMed).

    Hoopmann, Punge, Barysch, Westphal, Bückers, Opazo, Bethani, Lauterbach, Hell, Rizzoli: "Endosomal sorting of readily releasable synaptic vesicles." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 44, pp. 19055-60, (2010) (PubMed).

    Yamada, Padilla-Parra, Park, Itoh, Chaineau, Monaldi, Cremona, Benfenati, De Camilli, Coppey-Moisan, Tramier, Galli, Takei: "Dynamic interaction of amphiphysin with N-WASP regulates actin assembly." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 34244-56, (2009) (PubMed).

    Ferguson, Brasnjo, Hayashi, Wölfel, Collesi, Giovedi, Raimondi, Gong, Ariel, Paradise, Otoole, Flavell, Cremona, Miesenböck, Ryan, De Camilli: "A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis." in: Science (New York, N.Y.), Vol. 316, Issue 5824, pp. 570-4, (2007) (PubMed).

    Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

  • 抗原

    Dynamin 1, 2, 3

    别名

    Dynamin 1/2/3

    背景

    Synonyms: dynamin 1, dynamin 2, dynamin 3

    Antigen Information: K.D. Dynamins are GTPases involved in endocytosis

    UniProt

    P21575
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