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QKI 抗体 (AA 1-341)

This anti-QKI antibody is a 小鼠 单克隆 antibody detecting QKI in WB, IHC, IF 和 ICC. Suitable for 人.
产品编号 ABIN1741377
发货至: 中国

Quick Overview for QKI 抗体 (AA 1-341) (ABIN1741377)

抗原

See all QKI 抗体
QKI (Protein Quaking (QKI))

适用

  • 48
  • 16
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1

宿主

  • 28
  • 25
  • 1
小鼠

克隆类型

  • 28
  • 26
单克隆

标记

  • 35
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
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This QKI antibody is un-conjugated

应用范围

  • 52
  • 36
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  • 8
  • 7
  • 2
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

S147-6
  • 抗原表位

    • 18
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-341

    特异性

    Detects ~36-38 kDa.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein G Purified

    免疫原

    Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.

    亚型

    IgG2b
  • 应用备注

    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN1741377 was sufficient for detection of Pan-QKI in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    QKI (Protein Quaking (QKI))

    别名

    QKI

    背景

    QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.

    基因ID

    9444

    UniProt

    Q96PU8
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