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Neuroligin 1 抗体 (AA 718-843) (PE)

This PE-conjugated 小鼠 单克隆 anti-Neuroligin 1 antibody (Clone S97A-31) specifically detects Neuroligin 1 in WB, IHC, ICC 和 IF. The antibody is reactive with 大鼠 samples.
产品编号 ABIN1741321
发货至: 中国
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Quick Overview for Neuroligin 1 抗体 (AA 718-843) (PE) (ABIN1741321)

抗原

See all Neuroligin 1 (NLGN1) 抗体
Neuroligin 1 (NLGN1)

适用

  • 46
  • 42
  • 25
大鼠

宿主

  • 37
  • 30
  • 1
小鼠

克隆类型

  • 41
  • 27
单克隆

标记

  • 24
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuroligin 1 antibody is conjugated to PE

应用范围

  • 52
  • 27
  • 26
  • 17
  • 14
  • 13
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

S97A-31
  • 抗原表位

    • 23
    • 16
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-843

    特异性

    Detects ~120 kDa. Does not cross-react with other Neuroligins.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein G Purified

    免疫原

    Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) >40% identity with Neuroligin-2 and -3.

    亚型

    IgG1
  • 应用备注

    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    说明

    2 μg/ml of ABIN1741321 was sufficient for detection of Neuroligin-1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    Neuroligin 1 (NLGN1)

    别名

    Neuroligin 1

    背景

    Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.

    基因ID

    116647

    UniProt

    Q62765

    途径

    Synaptic Membrane, Synaptic Vesicle Exocytosis
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