VDAC1 抗体 (AA 1-283) (Atto 390)
Quick Overview for VDAC1 抗体 (AA 1-283) (Atto 390) (ABIN1741216)
抗原
See all VDAC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-283
-
特异性
- Detects ~30 kDa. Does not cross-react with VDAC2 or VDAC3 (based on KO validation results).
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Protein G Purified
-
免疫原
- Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical). Rat: 98% identity (279/283 amino acids identical) >60% identity with VDAC2 and VDAC3.
-
亚型
- IgG2a
-
-
-
-
应用备注
-
- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
-
说明
-
1 μg/ml of ABIN1741216 was sufficient for detection of VDAC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Conjugated antibodies should be stored at 4°C
-
-
- VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
-
别名
- VDAC1
-
背景
- Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.
-
基因ID
- 7416
-
UniProt
- P21796
抗原
-