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VDAC1 抗体 (AA 1-283) (Atto 390)

This anti-VDAC1 antibody is a 小鼠 单克隆 antibody detecting VDAC1 in WB, IHC, IF 和 ICC. Suitable for 人.
产品编号 ABIN1741216
发货至: 中国

Quick Overview for VDAC1 抗体 (AA 1-283) (Atto 390) (ABIN1741216)

抗原

See all VDAC1 抗体
VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

适用

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宿主

  • 73
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小鼠

克隆类型

  • 62
  • 39
单克隆

标记

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This VDAC1 antibody is conjugated to Atto 390

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

S152B-23
  • 抗原表位

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    AA 1-283

    特异性

    Detects ~30 kDa. Does not cross-react with VDAC2 or VDAC3 (based on KO validation results).

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein G Purified

    免疫原

    Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical). Rat: 98% identity (279/283 amino acids identical) >60% identity with VDAC2 and VDAC3.

    亚型

    IgG2a
  • 应用备注

    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN1741216 was sufficient for detection of VDAC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Conjugated antibodies should be stored at 4°C
  • 抗原

    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

    别名

    VDAC1

    背景

    Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.

    基因ID

    7416

    UniProt

    P21796
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